{"product_id":"biolegend-339708","title":"Biolegend, 339708, Spark YG™ 581 anti-human CD300e (IREM-2, CMRF35-A5) Antibody, 100tests","description":"\u003cp\u003eIREM-2 (immune receptor expressed by myeloid cells 2), also known as CMRF35-A5, LMIR6, CD300Le or CD300e, is a 34 kD type I single transmembrane glycoprotein. It is a member of the CD300 family and of the Ig-superfamily. IREM-2 is expressed on monocyte and myeloid dendritic cells, but not on granulocytes and lymphoid dendritic cells. IREM-2 is an activating receptor through interaction with DAP12.\u003cbr\u003e\n100tests\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nImmunogen: IREM-IgG fusion protein\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography and conjugated with Spark YG™ 581 under optimal conditions.\u003cbr\u003e\nConcentration: Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. * Spark YG™ 581 has a maximum excitation of 562 nm and a maximum emission of 581 nm.\u003cbr\u003e\nExcitation Laser: Green Laser (532 nm)\/Yellow-Green Laser (561 nm)\u003cbr\u003e\nApplication Notes: Additional reported applications include: immunoprecipitation and stimulation of TNF-a production by monocytes\u003cbr\u003e\nApplication References(PubMed link indicates BioLegend citation): Aguilar H, et al. 2004. J. Immunol. 173:6703 Gasiorowski RE, et al. 2013. Immunol Lett. 149:93. PubMed\u003cbr\u003e\nRRID: AB_3083320 (BioLegend Cat. No. 339707) AB_3083320 (BioLegend Cat. No. 339708)\u003cbr\u003e\nStructure: 34 kD, type I transmembrane glycoprotein, CD300 family, Ig superfamily\u003cbr\u003e\nDistribution: Monocytes, macrophages, dendritic cells\u003cbr\u003e\nFunction: Activation of myeloid cells\u003cbr\u003e\nCell Type: Dendritic cells, Macrophages, Monocytes\u003cbr\u003e\nBiology Area: Immunology\u003cbr\u003e\nMolecular Family: CD Molecules\u003cbr\u003e\nAntigen References: 1. Aguilar H, et al. 2004. J. Immunol. 173:6703\u003cbr\u003e\nGene ID: 342510\u003cbr\u003e\nUniProt: View information about CD300e on UniProt.org\u003cbr\u003e\nClone: UP-H2\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: CD300e, CMRF35-A5, LMIR6\u003cbr\u003e\nIsotype: Mouse IgG1, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46864079814825,"sku":"339708","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/biolegend-339708","provider":"Iright","version":"1.0","type":"link"}