{"product_id":"biolegend-341411","title":"Biolegend, 341411, APC\/Fire™ 750 anti-human CD79b (Igβ) Antibody, 25tests","description":"\u003cp\u003eCD79 is a heterodimeric molecule comprised of an α-chain (CD79a) and β-chain (CD79b). A 37-39 kD type I integral membrane protein CD79b is non-covalently associated with CD79a and cell surface IgM to form the B-cell receptor (BCR) complex. CD79b is expressed on the surface of surface Ig (sIg)-positive B cells and in the cytoplasm of sIg-negative B cells. It is essential for signal transduction after surface Ig crosslinking.\u003cbr\u003e\n25tests\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nReported Reactivity: African Green, Baboon, Cynomolgus, Rhesus\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography and conjugated with APC\/Fire™ 750 under optimal conditions.\u003cbr\u003e\nConcentration: Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells or 5 µl per 100 µl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. * APC\/Fire™ 750 has a maximum excitation of 650 nm and a maximum emission of 774 nm.\u003cbr\u003e\nExcitation Laser: Red Laser (633 nm)\u003cbr\u003e\nApplication References(PubMed link indicates BioLegend citation): Nakamura T, et al. 1992. P. Natl. Acad. Sci. USA 89:8522. Garcia Vela J, et al. 1999. Leukemia. 13:1501. Yoshino N, et al. 2000. Exp. Anim. (Tokyo) 49:97. (FC) Rossi EA, et al. 2014. PLoS One. 9:98315. PubMed\u003cbr\u003e\nRRID: AB_2650918 (BioLegend Cat. No. 341412)\u003cbr\u003e\nStructure: 37-39 kD type I integral membrane protein, associate with CD79a and cell surface IgM to form the B-cell receptor (BCR) complex, Ig superfamily.\u003cbr\u003e\nDistribution: B cells\u003cbr\u003e\nFunction: From BCR complex, signal transduction\u003cbr\u003e\nCell Type: B cells\u003cbr\u003e\nBiology Area: Immunology\u003cbr\u003e\nMolecular Family: CD Molecules\u003cbr\u003e\nAntigen References: 1. Zola H, et al. Eds. 2007. Leukocyte and Stromal Cell Molecules:The CD Markers. A John Wiley \u0026amp; Sons Inc. 2. Dylke J, et al. 2007. Immunol. Lett. 112:47\u003cbr\u003e\nGene ID: 974\u003cbr\u003e\nUniProt: View information about CD79b on UniProt.org\u003cbr\u003e\nClone: CB3-1\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nWorkshop: VI CD79.1\u003cbr\u003e\nOther Names: Igb, Igβ (Ig-beta), B29\u003cbr\u003e\nIsotype: Mouse IgG1, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46862963245225,"sku":"341411","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/biolegend-341411","provider":"Iright","version":"1.0","type":"link"}