{"product_id":"biolegend-342327","title":"Biolegend, 342327, Spark YG™ 570 anti-human CD66a\/c\/e Antibody, 25μg","description":"\u003cp\u003eThe ASL-32 mAb reacts with an antigen epitope shared by CD66a, c and e. CD66a\/c\/e are members of the CEA (carcinoembryonic antigen) family of the Ig superfamily. CD66 plays a role in hemophilic and heterophilic adhesion. CD66a, also known as CEACAM1 and BGP (biliary glycoprotein), is mainly expressed on granulocytes, binds to CD66a, c, e, and CD62E. CD66c (known as CEACAM6, NCA) is expressed on granulocytes and epithelial cells. The ligands of CD66c are CD66a-e, CD62E and Galectins. CD66e molecule is also called CEA or CEACAM5, and is primarily found on epithelial cells. CD66e binds to CD66a, c and e.\u003cbr\u003e\n25μg\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography and conjugated with Spark YG™ 570 under optimal conditions.\u003cbr\u003e\nConcentration: 0.5 mg\/mL\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: IHC-P - Quality tested FC - Verified\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration range of 5 - 10 µg\/mL is suggested. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. * Spark YG™ 570 has a maximum excitation of 555 nm and a maximum emission of 570 nm.\u003cbr\u003e\nExcitation Laser: Green Laser (532 nm)\/Yellow-Green Laser (561 nm)\u003cbr\u003e\nApplication References(PubMed link indicates BioLegend citation): Shey MS, et al. 2012. J Immunol Methods. 376:79. PubMed.\u003cbr\u003e\nRRID: AB_2904361 (BioLegend Cat. No. 342327) AB_2904361 (BioLegend Cat. No. 342328)\u003cbr\u003e\nStructure: Member of the CEA (carcinoembryonic antigen) family of the Ig superfamily\u003cbr\u003e\nDistribution: Granulocytes, epithelial cells\u003cbr\u003e\nFunction: Homophilic and heterophilic adhesion\u003cbr\u003e\nLigand\/Receptor: CD66a-e, CD62E, galectins\u003cbr\u003e\nCell Type: Epithelial cells, Granulocytes\u003cbr\u003e\nBiology Area: Immunology\u003cbr\u003e\nMolecular Family: Adhesion Molecules, CD Molecules\u003cbr\u003e\nAntigen References: 1. Zola H, et al. 2007. Leukocyte and Stromal Cell Molecules:The CD Markers. Wiley-Liss. A John Wiley \u0026amp; Sons Inc. Publication\u003cbr\u003e\nGene ID: 634\u003cbr\u003e\nUniProt: View information about CD66a CD66c CD66e on UniProt.org\u003cbr\u003e\nClone: ASL-32\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: CEACAM1\/5\/6, BGP, NCA\u003cbr\u003e\nIsotype: Mouse IgG2b, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46862543585449,"sku":"342327","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/biolegend-342327","provider":"Iright","version":"1.0","type":"link"}