{"product_id":"biolegend-348103","title":"Biolegend, 348103, PE anti-human TCR Vβ8 Antibody, 25tests","description":"\u003cp\u003eVβ8 T cell receptor (TCR Vβ8) is a variant of the TCR β chain which is heterodimerized with TCR α chain and expressed on a subset of T cells. In association with CD3 complex, TCR α\/β functions recognition of antigen and initiating T cell mediated immune responses. Human Vβ8 has been described as the target of the streptococcal mitogenic exotoxin z (SMEZ) and SMEZ-2.\u003cbr\u003e\n25tests\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.\u003cbr\u003e\nConcentration: Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.\u003cbr\u003e\nExcitation Laser: Blue Laser (488 nm)Green Laser (532 nm)\/Yellow-Green Laser (561 nm)\u003cbr\u003e\nApplication References(PubMed link indicates BioLegend citation): Lavoie PM, et al. 2005. Int. Immunol. 17:931 Okas M, et al. 2010. J. Immunother. 33:96\u003cbr\u003e\nProduct Citations: Ge Y, et al. 2019. J Immunol. 203:2827. PubMed Zhong S, et al. 2013. Proc Natl Acad Sci U S A. 110:6973. PubMed Malecek K, et al. 2013. J Immunol Methods. 392:1. PubMed Li F, et al. 2022. Nat Commun. 13:4334. PubMed\u003cbr\u003e\nRRID: AB_10549976 (BioLegend Cat. No. 348104)\u003cbr\u003e\nStructure: Immunoglobulin superfamily, associate with TCR Vα chain and CD3 complex\u003cbr\u003e\nDistribution: Subset of T cells\u003cbr\u003e\nFunction: Antigen recognition\u003cbr\u003e\nLigand\/Receptor: MHC-Peptide complex\u003cbr\u003e\nCell Type: T cells\u003cbr\u003e\nBiology Area: Adaptive Immunity, Immunology\u003cbr\u003e\nMolecular Family: TCRs\u003cbr\u003e\nAntigen References: 1. Proft T, et al. 1999. J. Exp. Med. 189:89. 2. Kelsen J, et al. 2004. Scand. J. Gastroenterol. 39:238.\u003cbr\u003e\nGene ID: 6957\u003cbr\u003e\nUniProt: View information about TCR Vbeta8 on UniProt.org\u003cbr\u003e\nClone: JR2 (JR.2)\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: Vbeta8\u003cbr\u003e\nIsotype: Mouse IgG2b, κ\u003cbr\u003e\nQ: What type of PE do you use in your conjugates?\u003cbr\u003e\nA: We use R-PE in our conjugates.\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866115887273,"sku":"348103","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/biolegend-348103","provider":"Iright","version":"1.0","type":"link"}