{"product_id":"biolegend-354117","title":"Biolegend, 354117, Alexa Fluor® 700 anti-human CD89 Antibody, 25tests","description":"\u003cp\u003eCD89, also known as FcαR, is a 55-100 kD glycosylated protein.  It belongs to the immunoglobulin gene family.  It is expressed on granulocytes, monocytes, and macrophages but is absent on T cells.  It can interact with IgA aggregates and plays an important role in IgA mediated immune responses.\u003cbr\u003e\n25tests\u003cbr\u003e\nVerified Reactivity: Human, Cynomolgus, Rhesus\u003cbr\u003e\nReported Reactivity: African Green, Baboon\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nImmunogen: Ag8.653 myeloma cells\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 700 under optimal conditions.\u003cbr\u003e\nConcentration: Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood. * Alexa Fluor® 700 has a maximum emission of 719 nm when it is excited at 633 nm \/ 635 nm. Prior to using Alexa Fluor® 700 conjugate for flow cytometric analysis, please verify your flow cytometer's capability of exciting and detecting the fluorochrome.Alexa Fluor® and Pacific Blue™ are trademarks of Life Technologies Corporation.View full statement regarding label licenses\u003cbr\u003e\nExcitation Laser: Red Laser (633 nm)\u003cbr\u003e\nApplication References(PubMed link indicates BioLegend citation): Monteiro RC, et al. 1992. J. Immunol. 148:1764. Shen L. 1992. J. Leukoc. Biol. 51:373. Schlossman S, et al. Eds. 1995. Leucocyte Typing V. Oxford University Press. New York. Rogers KA, et al. 2004. Immunology 113:178.\u003cbr\u003e\nRRID: AB_2750066 (BioLegend Cat. No. 354117) AB_2750067 (BioLegend Cat. No. 354118)\u003cbr\u003e\nStructure: Member of the immunoglobulin gene family and is a transmembrane glycoprotein, 55-100 kD\u003cbr\u003e\nDistribution: Granulocytes, neutrophils, eosinophils, monocytes, macrophages\u003cbr\u003e\nFunction: Interacts with IgA opsonized targets and induces immunological processes such as phagocytosis, ADCC, and release of inflammatory mediators\u003cbr\u003e\nLigand\/Receptor: IgA (monomeric, dimeric, polymeric and secretory IgA)\u003cbr\u003e\nCell Type: Eosinophils, Granulocytes, Macrophages, Monocytes, Neutrophils\u003cbr\u003e\nBiology Area: Immunology\u003cbr\u003e\nMolecular Family: CD Molecules, Fc Receptors\u003cbr\u003e\nAntigen References: 1. Patry C, et al. 1996. J. Immunol. 156:4442. 2. de Wit, et al. 1995. J. Immunol. 155:1203. 3. Honorio-França AC, et al. 2001. J. Leukoc. Biol. 69:289.\u003cbr\u003e\nGene ID: 2204\u003cbr\u003e\nUniProt: View information about CD89 on UniProt.org\u003cbr\u003e\nClone: A59\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nWorkshop: V MR30\u003cbr\u003e\nOther Names: FcαR\u003cbr\u003e\nIsotype: Mouse IgG1, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46862523531433,"sku":"354117","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/biolegend-354117","provider":"Iright","version":"1.0","type":"link"}