{"product_id":"biolegend-360202","title":"Biolegend, 360202, Purified anti-human CD368 (CLEC4D) Antibody, 100μg","description":"\u003cp\u003eCD368 (CLEC4D), also known as CLEC6, is a 30 kD single pass type II transmembrane protein and member of the C-type lectin-like domain (CTLD) superfamily. CLEC4D is an endocytic receptor, probably involved in antigen presentation, cell adhesion, and cell signaling. CLEC4D is expressed by macrophages, monocytes, neutrophils, and a subset of dendritic cells and is upregulated by IL-6, IL-10, TNF-α, and IFN-γ.\u003cbr\u003e\n100μg\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nImmunogen: CLEC4D ectodomain:IgG Fc fusion protein\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography.\u003cbr\u003e\nConcentration: 0.5 mg\/ml\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C.\u003cbr\u003e\nApplication: FC - Quality testedICC - Verified\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nRRID: AB_2562508 (BioLegend Cat. No. 360202)\u003cbr\u003e\nStructure: Member of the C-type lectin-like domain (CTLD) superfamily, single pass type II transmembrane protein, 30 kD\u003cbr\u003e\nDistribution: Macrophages, monocytes, neutrophils, subset of dendritic cells; low expression in peripheral blood lymphocytes\u003cbr\u003e\nFunction: Endocytic receptor, probably involved in antigen presentation, cell adhesion, and cell signaling\u003cbr\u003e\nCell Type: Dendritic cells, Macrophages, Monocytes, Neutrophils\u003cbr\u003e\nBiology Area: Immunology, Innate Immunity\u003cbr\u003e\nMolecular Family: CD Molecules\u003cbr\u003e\nAntigen References: 1. Zhu LL, et al. 2013. Immunity 39:11. 2. Graham LM, et al. 2012. J. Biol. Chem. 287:25964. 3. Arce I, et al. 2004. Eur. J. Immunol. 34:210.\u003cbr\u003e\nGene ID: 338339\u003cbr\u003e\nUniProt: View information about CD368 on UniProt.org\u003cbr\u003e\nClone: 9B9\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nWorkshop: HCDM listed\u003cbr\u003e\nOther Names: C-type lectin domain family 4 member D, CLEC6, CLECSF8, MCL, MPCL, Dectin-3, CD368\u003cbr\u003e\nIsotype: Mouse IgG2b, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46862503215273,"sku":"360202","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/biolegend-360202","provider":"Iright","version":"1.0","type":"link"}