{"product_id":"biolegend-372303","title":"Biolegend, 372303, PE anti-human CD217 Antibody, 25tests","description":"\u003cp\u003eSix interleukin-17 (IL-17)-family (IL-17A-IL-17F) and five IL-17 receptor (IL-17R)-family (IL-17RA-IL-17RE) members have been reported in mammalian cells. IL-17RA (known as IL-17R, IL-17AR, CD217) is a 128-158 kD type I transmembrane glycoprotein. IL-17R binds to IL-17A (also known as IL-17, and CTLA-8, is a hallmarker of Th17 cells) and IL-17F and mediates the proinflammatory signals through interaction with IL-17RC or IL-17RD. IL-17R has broad tissue distribution, including fibroblasts, epithelial cells, endothelial cells, stromal cells, B cells, T cells, NK cells, monocytes and granulocytes.\u003cbr\u003e\n25tests\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nImmunogen: P3U1 cells stably transfected with CD217.\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.\u003cbr\u003e\nConcentration: Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.\u003cbr\u003e\nExcitation Laser: Blue Laser (488 nm)Green Laser (532 nm)\/Yellow-Green Laser (561 nm)\u003cbr\u003e\nRRID: AB_2632647 (BioLegend Cat. No. 372303) AB_2632648 (BioLegend Cat. No. 372304)\u003cbr\u003e\nStructure: 128-158 kD type I single transmembrane glycoprotein, homodimer or heterodimer with IL-17RC, or associate with IL-17RD.\u003cbr\u003e\nDistribution: Broad tissue distribution, including fibroblasts, epithelial cells, endothelial cells, stromal cells, B cells, T cells, NK cells, monocytes and granulocytes\u003cbr\u003e\nFunction: Binds IL-17 and mediate IL-17 induced inflammatory responses.\u003cbr\u003e\nLigand\/Receptor: IL-17A, IL-17F.\u003cbr\u003e\nCell Type: Eosinophils, Neutrophils\u003cbr\u003e\nBiology Area: Immunology\u003cbr\u003e\nMolecular Family: CD Molecules\u003cbr\u003e\nAntigen References: 1. Moseley TA, et al. 2003. Cytokine Growth Factor Rev. 14:155. 2. Rong Z, et al. 2009. Cell. Res. 19:208. 3. Toy D, et al. 2006. J. Immunol. 177:36.\u003cbr\u003e\nGene ID: 23765\u003cbr\u003e\nUniProt: View information about CD217 on UniProt.org\u003cbr\u003e\nClone: W15177A\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: IL-17R, IL-17RA, IL-17AR, IL-17 receptor\u003cbr\u003e\nIsotype: Mouse IgG2a, κ\u003cbr\u003e\nQ: What type of PE do you use in your conjugates?\u003cbr\u003e\nA: We use R-PE in our conjugates.\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866300272809,"sku":"372303","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/biolegend-372303","provider":"Iright","version":"1.0","type":"link"}