{"product_id":"biolegend-375507","title":"Biolegend, 375507, FITC anti-human CD20 Antibody, 25tests","description":"\u003cp\u003eCD20 (also known as B1 and Bp35) is a four transmembrane spanning protein measuring 33-37 kD. Expressed on pre-B cells, resting and activated B cells (not plasma cells), some follicular dendritic cells, and at low levels on a T cell subset. Involved in B-cell activation and is associated with a variety of Src family kinases.\u003cbr\u003e\n25tests\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nImmunogen: Human CD20 transfectant\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography and conjugated with FITC under optimal conditions.\u003cbr\u003e\nConcentration: Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nExcitation Laser: Blue Laser (488 nm)\u003cbr\u003e\nRRID: AB_2890822 (BioLegend Cat. No. 375507) AB_2890822 (BioLegend Cat. No. 375508)\u003cbr\u003e\nStructure: Four transmembrane protein (TM4SF), heavily phosphorylated after activation, 33-37 kD\u003cbr\u003e\nDistribution: B cell, T cell subsets\u003cbr\u003e\nFunction: B cell activation\u003cbr\u003e\nInteraction: The CD20 molecule is involved in B-cell activation and is associated with various Src family kinases (Lyn, Lck, Fyn).\u003cbr\u003e\nLigand\/Receptor: Src family tyrosine kinases, MHC class I, II, CD53, CD81, CD82\u003cbr\u003e\nCell Type: B cells, T cells\u003cbr\u003e\nBiology Area: Costimulatory Molecules, Immunology\u003cbr\u003e\nMolecular Family: CD Molecules\u003cbr\u003e\nAntigen References: Hultin LE, et al. 1993. Cytometry 14:196. Tedder T and Engel P. 1994. Immunol. Today 15:450.\u003cbr\u003e\nGene ID: 931\u003cbr\u003e\nUniProt: View information about CD20 on UniProt.org\u003cbr\u003e\nClone: S18015E\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: B1, Bp35\u003cbr\u003e\nIsotype: Mouse IgG2a, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866247221417,"sku":"375507","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/biolegend-375507","provider":"Iright","version":"1.0","type":"link"}