{"product_id":"biolegend-385702","title":"Biolegend, 385702, Purified anti-human CD69 Recombinant Antibody, 100μg","description":"\u003cp\u003eCD69, also known as activation inducer molecule (AIM), very early activation antigen (VEA), and MLR3, is a 27-33 kD type II transmembrane protein. It is a member of the C-type lectin family and expressed as a disulfide-linked homodimer. Other members of this receptor family include NKG2, NKR-P1 CD94, and Ly49. CD69 is transiently expressed on activated leukocytes including T cells, thymocytes, B cells, NK cells, neutrophils, and eosinophils. CD69 is constitutively expressed by a subset of medullary mature thymocytes, platelets, mantle B cells, and certain CD4+ T cells in germinal centers of normal lymph nodes. CD69 is involved in early events of lymphocyte, monocyte, and platelet activation, and has a functional role in redirected lysis mediated by activated NK cells.\u003cbr\u003e\n100μg\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nAntibody Type: Recombinant\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography.\u003cbr\u003e\nConcentration: 0.5 mg\/mL\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nApplication Notes: Clone QA18A26 can completely block the binding of clone FN50 on target cells.\u003cbr\u003e\nRRID: AB_2927999 (BioLegend Cat. No. 385702)\u003cbr\u003e\nStructure: C-type lectin, type II glycoprotein, 28\/32 kD\u003cbr\u003e\nDistribution: Activated T cells, B cells, NK cels, Granulocytes, thymocytes, platelets, Langerhans cells\u003cbr\u003e\nFunction: Lymphocyte, monocyte, and platelet activation, NK cell killing\u003cbr\u003e\nCell Type: B cells, Lymphocytes, NK cells, Platelets, T cells, Thymocytes\u003cbr\u003e\nBiology Area: Immunology\u003cbr\u003e\nMolecular Family: Adhesion Molecules, CD Molecules\u003cbr\u003e\nAntigen References: Schlossman S, et al. 1995. Leucocyte Typing V. Oxford University Press. Marzio R, et al. 1999. Immunopharmacology and immunotoxicology. 21:565-82.\u003cbr\u003e\nGene ID: 969\u003cbr\u003e\nUniProt: View information about CD69 on UniProt.org\u003cbr\u003e\nClone: QA18A26\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: Very Early Activation Antigen (VEA), Activation inducer molecule (AIM)\u003cbr\u003e\nIsotype: Mouse IgG1, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866180669609,"sku":"385702","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/biolegend-385702","provider":"Iright","version":"1.0","type":"link"}