{"product_id":"biolegend-394202","title":"Biolegend, 394202, Purified anti-human IL12RB2 Antibody, 100μg","description":"\u003cp\u003eIL12RB2 is a type I transmembrane protein that foms an heterodimer with IL12RB1 to produce the high affinity IL-12 receptor complex. IL12RB2 is expressed by activated T cells, TH1 cells, NK cells, B cells and plasma cells. Variants of this gene are associated with predisposition to various immune-related diseases.\u003cbr\u003e\n100μg\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nImmunogen: Human IL12RB2 transfected cells.\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography.\u003cbr\u003e\nConcentration: 0.5 mg\/ml\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nProduct Citations: Preechanukul A, et al. 2023. iScience. 107234:26. PubMed\u003cbr\u003e\nRRID: AB_2734483 (BioLegend Cat. No. 394202)\u003cbr\u003e\nStructure: Type I transmembrane protein, 3 isoforms, foms an heterodimer with IL12RB1\u003cbr\u003e\nDistribution: Activated T cells, TH1 cells, NK cells, B cells, plasma cells\u003cbr\u003e\nFunction: Role in TH1 differentiation\u003cbr\u003e\nLigand\/Receptor: IL-12\u003cbr\u003e\nCell Type: B cells, NK cells, Plasma cells, T cells, Th1\u003cbr\u003e\nBiology Area: Immunology\u003cbr\u003e\nMolecular Family: Cytokine\/Chemokine Receptors\u003cbr\u003e\nAntigen References: LaMere SA, et al. 2017. J Immunol. 199:3158 Prigione I, et al. 2016. Immunobiology. 221:291 de Paus RA, et al. 2013. Mol Immunol. 56:380 Airoldi I, et al. 2008. Blood. 112:750\u003cbr\u003e\nGene ID: 3595\u003cbr\u003e\nUniProt: View information about IL12RB2 on UniProt.org\u003cbr\u003e\nClone: S16020B\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: Interleukin-12 receptor subunit beta-2\u003cbr\u003e\nIsotype: Mouse IgG2a, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866227462313,"sku":"394202","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/biolegend-394202","provider":"Iright","version":"1.0","type":"link"}