{"product_id":"biolegend-398803","title":"Biolegend, 398803, PE anti-human CD56 (NCAM) Recombinant Antibody, 25tests","description":"\u003cp\u003eCD56 is a single transmembrane glycoprotein also known as NCAM (Neural Cell Adhesion Molecule), Leu-19, or NKH1. It is a member of the Ig superfamily. The 140 kD isoform is expressed on NK cells and NK-T cells. CD56 is also expressed in the brain (cerebellum and cortex) and at neuromuscular junctions. Certain large granular lymphocyte (LGL) leukemias, small-cell lung carcinomas, neuronal derived tumors, myelomas, and myeloid leukemias also express CD56. CD56 plays a role in homophilic and heterophilic adhesion via binding to itself or heparin sulfate.\u003cbr\u003e\n25tests\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nAntibody Type: Recombinant\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.\u003cbr\u003e\nConcentration: Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood.\u003cbr\u003e\nExcitation Laser: Blue Laser (488 nm)Green Laser (532 nm)\/Yellow-Green Laser (561 nm)\u003cbr\u003e\nRRID: AB_2820070 (BioLegend Cat. No. 398803) AB_2820071 (BioLegend Cat. No. 398804)\u003cbr\u003e\nStructure: Ig superfamily, single transmembrane or GPI-anchored glycoprotein\u003cbr\u003e\nDistribution: NK cells, T subset, neural tissue, some LGL and myeloid leukemias\u003cbr\u003e\nFunction: Adhesion\u003cbr\u003e\nLigand\/Receptor: Heparin sulfate\u003cbr\u003e\nCell Type: B cells, Leukemia, Mesenchymal Stem Cells, Neurons, T cells\u003cbr\u003e\nBiology Area: Cell Adhesion, Cell Biology, Costimulatory Molecules, Immunology, Innate Immunity, Neuroscience, Stem Cells, Synaptic Biology\u003cbr\u003e\nMolecular Family: Adhesion Molecules, CD Molecules\u003cbr\u003e\nAntigen References: Rosental B, et al. 2011. J Immunol. 187:5693. PubMed Correia DV, et al. 2011. Blood. 118:992. PubMed Schlecker E, et al. 2014. Cancer Res. 74:3429. PubMed Snyder JM, et al. 2014. PLoS One. 9:e107257. PubMed Siebert N, et al. 2014. PLoS One. 9:e107692. PubMed Rider P, et al. 2015. J Immunol. 195:1705-12. PubMed Davis ZB, et al. 2011. J Vis Exp. 49: 2668. PubMed Robin JD, et al. 2015. J Vis Exp. 95: 52307. PubMed Ames E, et al. 2015. J Immunol. 195: 4010-9. PubMed Laroni A, et al. 2016. J Autoimmun. 72:8-18. PubMed Pachnio A, et al. 2016. PLoS Pathog. 12:e1005832. PubMed Wouters K, et al. 2017. Sci Rep. 7:42665. PubMed\u003cbr\u003e\nGene ID: 4684\u003cbr\u003e\nUniProt: View information about CD56 on UniProt.org\u003cbr\u003e\nClone: QA18A21\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: Leu-19, NKH1\u003cbr\u003e\nIsotype: Mouse IgG1, κ\u003cbr\u003e\nQ: What type of PE do you use in your conjugates?\u003cbr\u003e\nA: We use R-PE in our conjugates.\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866178801833,"sku":"398803","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/biolegend-398803","provider":"Iright","version":"1.0","type":"link"}