{"product_id":"biolegend-399709","title":"Biolegend, 399709, Brilliant Violet™ 421 anti-human TGF-β Receptor II Antibody, 25tests","description":"\u003cp\u003eTransforming growth factor beta receptor 2 (TGFbR2 or TGFbRII) forms a heterodimeric complex on the cell surface with TGFbR1. TGFbR2 binds TGF-beta and is important for cell proliferation, wound healing, immunosuppression, and tumorigenesis.\u003cbr\u003e\n25tests\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Rat\u003cbr\u003e\nImmunogen: TGFbR2 protein (aa 1-243) expressing transfectants\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography and conjugated with Brilliant Violet 421™ under optimal conditions.\u003cbr\u003e\nConcentration: Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. Brilliant Violet 421™ excites at 405 nm and emits at 421 nm. The standard bandpass filter 450\/50 nm is recommended for detection. Brilliant Violet 421™ is a trademark of Sirigen Group Ltd.Learn more about Brilliant Violet™. This product is subject to proprietary rights of Sirigen Inc. and is made and sold under license from Sirigen Inc. The purchase of this product conveys to the buyer a non-transferable right to use the purchased product for research purposes only. This product may not be resold or incorporated in any manner into another product for resale. Any use for therapeutics or diagnostics is strictly prohibited. This product is covered by U.S. Patent(s), pending patent applications and foreign equivalents.\u003cbr\u003e\nExcitation Laser: Violet Laser (405 nm)\u003cbr\u003e\nRRID: AB_2936678 (BioLegend Cat. No. 399709) AB_2936678 (BioLegend Cat. No. 399710)\u003cbr\u003e\nDistribution: B cells, T cells, monocytes, and granulocytes.\u003cbr\u003e\nLigand\/Receptor: TGFbR2 forms a heterodimeric complex with TGFbR1 and binds TGF-β.\u003cbr\u003e\nCell Type: B cells, Monocytes, T cells\u003cbr\u003e\nBiology Area: Immunology\u003cbr\u003e\nMolecular Family: Cytokines\/Chemokines\u003cbr\u003e\nAntigen References: Horbelt D, et al. 2010. J Cell Sci. 123:4340-50. Wei CY, et al. 2015. Int J Clin Exp Pathol. 8:14619-29. Numata S, et al. 2008. J Psychiatr Res. 42:425-32.\u003cbr\u003e\nGene ID: 7048\u003cbr\u003e\nUniProt: View information about TGF-beta Receptor II on UniProt.org\u003cbr\u003e\nClone: W17055E\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: TGFRII, TGFR2, TGFR-2, TβRII, TGFbeta-RII, TGF-Beta Receptor Type II, TGF-Beta Receptor Type-2\u003cbr\u003e\nIsotype: Rat IgG2b, κ\u003cbr\u003e\nQ: What is the F\/P ratio range of our BV421™ format antibody reagents?\u003cbr\u003e\nA: It is lot-specific. On average it ranges between 2-4.\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866311479465,"sku":"399709","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/biolegend-399709","provider":"Iright","version":"1.0","type":"link"}