{"product_id":"biolegend-422304","title":"Biolegend, 422304, Human TruStain FcX™, GMP, 200tests","description":"\u003cp\u003eHuman Fc receptors (FcRs) are expressed on a variety of cells, such as monocytes, granulocytes, B cells and dendritic cells. The cells with FcR expression sometimes give false positive or false negative results of immunofluorescent staining due to the FcRs-mediated Ig Fc binding. Human TruStain FcX™ is specially formulated for blocking the FcR-involved unwanted staining without interfering with antibody-mediated specific staining of human cells. Human TruStain FcX™ is compatible with flow cytometric staining with anti-human CD16 (clone 3G8), CD32 (clone FUN-2), and CD64 (clone 10.1) antibodies.\u003cbr\u003e\n200tests\u003cbr\u003e\nFormulation: Human IgG in PBS containing 0.09% sodium azide\u003cbr\u003e\nStorage \u0026amp; Handling: Store between 2°C-8°C\u003cbr\u003e\nApplication: FC - Quality tested\u003cbr\u003e\nRecommended Usage: It is recommended to add 5 µl of Human TruStain FcX™ per million cells in 100 µl staining volume, mix and incubate at room temperature for 5-10 minutes prior to staining with antibody of interest. It is not necessary to wash cells between these blocking and immunostaining steps.\u003cbr\u003e\nApplication Notes: This buffer contains specialized human IgG in PBS containing 0.09% sodium azide. It is not recommended to be used for staining human IgG. Handle as biohazard agent.\u003cbr\u003e\nApplication References(PubMed link indicates BioLegend citation): de la Cruz J, et al. 2011. J. Immunol. 186:2282. PubMed Luo L, et al. 2011. Exp Mol Pathol. 91:596. PubMed Szerlip NJ, et al. 2012. PNAS. 109:3041. PubMed Bromley SK, et al. 2013. J. Immunol. 190:970. PubMed Trujilo G, et al. 2013. J. Immunol. 191:848. PubMed Edin S, et al. 2013. PLoS One. 18:74982. PubMed Euzebio Alves VT, et al. 2013. Infect Immun. 81:4399. PubMed Borg ZD, et al. 2014. J. Immunol. 192:189. PubMed Klingenberg R, et al. 2014. Eur Heart J. PubMed Lines JL, et al. 2014. Cancer Res. 74:1924. PubMed Decker D, et al. 2014. Lupus. 23:802. PubMed Jitschin R, et al. 2014. Blood. 123:2663. PubMed Anderson ME Jr, et al. 2014. Otolaryngol Head Neck Surg. 150:880. PubMed Giurisato E, et al. 2014. Mol Biol Cell. 25:1769. PubMed Shi J, et al. 2014. Blood. 123:4015. PubMed Kusner LL, et al. 2014. PLoS One. 9:102231. PubMed Fujisawa D, et al. 2014. J Allergy Clin Immunol. 134:622. PubMed Bhardwaj N, et al. 2014. J Virol. 88:11108. PubMed Lieber S, et al. 2014. Mol Pharmacol. 87:162. PubMed Olagnier D, et al. 2014. PLoS Pathog. 10:1004566. PubMed Punyadee N, et al. 2015. J Virol. 89:1587. PubMed Vuong TT, et al. 2015. J Histochem Cytochem. 63:280. PubMed Klingenberg R, et al. 2015. Eur Heart J. 36:1041. PubMed Wilkinson-Ryan I, et al. 2015. PLoS One.10:125851. PubMed\u003cbr\u003e\nMolecular Family: Fc Receptors\u003cbr\u003e\nGene ID: NA\u003cbr\u003e\nOther Names: Fc Blocker, FcγR blocker, Fc inhibitor\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866528895145,"sku":"422304","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/biolegend-422304","provider":"Iright","version":"1.0","type":"link"}