{"product_id":"biolegend-431308","title":"Biolegend, 431308, LEGEND MAX™ Mouse IL-6 ELISA Kit, 5precoatedplates","description":"\u003cp\u003eMouse IL-6 (other names include B-cell Stimulatory Factor 2, Interferon Beta-2, Hybridoma Growth Factor, and Cytotoxic T-Cell Differentiation Factor) plays an essential role in the final differentiation of B-cells into imunoglobin-secreting cells, it induces myeloma and plasmacytoma growth, induces nerve cell differentiation, and in hepatocytes it induces acute phase reactant proteins. IL-6 is expressed by T cells, B cells, monocytes, fibroblasts, hepatocytes, endothelial cells, and keratinocytes. Current research supports IL-6 as playing a critical role in many physiological and pathological conditions, including autoimmune diseases and rheumatoid arthritis.  BioLegend’s LEGEND MAX™ Mouse IL-6 ELISA Kit is a sandwich Enzyme-Linked Immunosorbent Assay (ELISA), in which, a Mouse IL-6 specific monoclonal antibody is pre-coated on a 96-well strip-well plate.  BioLegend’s LEGEND MAX™ Mouse IL-6ELISA Kit is specifically designed for the accurate quantitation of Mouse IL-6 from cell culture supernatant, serum, plasma or other bodily fluids. It is ready-to-use, accurate, and sensitive.\u003cbr\u003e\n5precoatedplates\u003cbr\u003e\nVerified Reactivity: Mouse\u003cbr\u003e\nApplication: ELISA\u003cbr\u003e\nApplication References(PubMed link indicates BioLegend citation): Liang G, et al. 2009. Eur J Med Chem. 44:915. PubMed\u003cbr\u003e\nProduct Citations: Weng SW, et al. 2023. Diabetologia. 66:913. PubMed Schwarz A, et al. 2023. Front Immunol. 14:1038689. PubMed Thirunavukkarasu M, et al. 2023. Cells. 12:. PubMed Sun Q, et al. 2023. Transl Neurosci. 14:20220273. PubMed Lliberós C, et al. 2021. Front Cell Dev Biol. 8:628473. PubMed Shi Z, et al. 2022. Br J Pharmacol. 179:5209. PubMed Wang Y, et al. 2022. Nat Commun. 13:7629. PubMed Wei K, et al. 2023. Signal Transduct Target Ther. 8:22. PubMed Oswal N, et al. 2023. Life (Basel). 13: . PubMed Liang G, et al. 2009. Eur J Med Chem. 44:915. PubMed Afraei S, et al. 2018. Cent Eur J Immunol. 43:9. PubMed Au DT, et al. 2018. Mediators Inflamm. 2018:7902841. PubMed Du L, et al. 2022. Aging (Albany NY). 14:6626. PubMed Yin Y, et al. 2022. Front Pharmacol. 13:882924. PubMed Wu D, et al. 2022. Cell Death Dis. 13:731. PubMed Lliberós C, et al. 2021. Sci Rep. 0.651388889. PubMed Park HB, et al. 2020. Oncoimmunology. 9:1772663. PubMed Wu H, et al. 2019. Autophagy. :1. PubMed Lin CC, et al. 2021. Iran J Basic Med Sci. 24:1146. PubMed Kessler SP, et al. 2018. J Histochem Cytochem. 66:273. PubMed Xu X, et al. 2018. Cell. 175:1336. PubMed Assi M, et al. 2017. Biochem Biophys Res Commun. 10.1016\/j.bbrc.2017.06.158. PubMed Tian M, et al. 2020. Cell Rep. 108297:33. PubMed Chen H, et al. 2021. Invest Ophthalmol Vis Sci. 62:11. PubMed Dossat AM, et al. 2017. FASEB J. 31:2492. PubMed Kueanjinda P, Palaga S 2015. Sci Rep. 5: 12784. PubMed Song J, et al. 2020. Mol Med Rep. 1.400694444. PubMed Lu Q, et al. 2022. Biomed Res Int. 2022:9427076. PubMed Su L, et al. 2019. EMBO J. 38:. PubMed Wang X, et al. 2022. Front Cell Infect Microbiol. 12:839592. PubMed\u003cbr\u003e\nSensitivity: 2 pg\/mL\u003cbr\u003e\nStandard Range: 7.8-500 pg\/mL\u003cbr\u003e\nCell Sources: T cells, B cells, macrophages, bone marrow stromal cells, fibroblasts, keratinocytes, mesangium, astrocytes, endothelial cells\u003cbr\u003e\nBiology Area: Immunology, Innate Immunity, Stem Cells\u003cbr\u003e\nMolecular Family: Cytokines\/Chemokines\u003cbr\u003e\nGene ID: 16193\u003cbr\u003e\nUniProt: View information about IL-6 on UniProt.org\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: IL-6 Pre-coated ELISA Kit\u003cbr\u003e\nQ: In your LEGEND MAX™ ELISA Kits, there is a step that calls for washing the plates before adding sample. What is the purpose of this step?\u003cbr\u003e\nA: We typically use a stabilizer for pre-coated plates. The additional washing step is designed to remove these components before you start the assay. If you do not perform the washing, the effect on assay performance is negligible.\u003cbr\u003e\nQ: I have multiple LEGEND MAX™ ELISA kits that I want to run simultaneously. Can I use the same wash buffer for all the kits?\u003cbr\u003e\nA: The wash buffer provided in all our LEGEND MAX™ kits is the same and the part numbers on the wash buffer bottles in these kits should be identical. For ELISA MAX™ Deluxe and ELISA MAX™ Standard Sets, we provide a recipe for the wash buffer on each kit’s technical data sheet. This recipe is the same for all ELISA MAX™ sets.\u003cbr\u003e\nQ: For some of your ELISA kits, why do my serum samples require dilution with assay buffer?\u003cbr\u003e\nA: In some cases, dilution with assay buffer is required to minimize the matrix difference between the samples and the standards to achieve better accuracy.\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46864129687721,"sku":"431308","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/biolegend-431308","provider":"Iright","version":"1.0","type":"link"}