{"product_id":"biolegend-433704","title":"Biolegend, 433704, ELISA MAX™ Deluxe Set Mouse IL-23, 5plates","description":"\u003cp\u003eCytokine detection IL-12, IL-23 and IL-35 share common subunits, utilizing combinations of p40, p19 and p35 proteins. Caution must be used when selecting antibodies and assays when specific identification, measurement, as well as activation state discrimination, is required.  1. Active IL-12 consists of two subunits: p40 + p35. 2. p40 can also exist as a monomer (IL-12 p40) or a homodimer (IL-12 p80). 3. Besides contributing to IL-12, p40 is also found in IL-23, a heterodimer of p40 and p19. 4. Similarly, p35 not only contributes to IL-12, but is also found in the heterodimer IL-35 (p35 and EBI3).  Note that assays using antibodies specific for the p40 subunit will be unable to discriminate between the active IL-12, monomeric p40, dimeric p40, and IL-23; likewise, assays using p35 detection alone will pick up both IL-12 (heterodimer) and IL-35. BioLegend ELISA assays ELISA Development Systems Engineered for Sensitive, Precise and Reliable Serum and Plasma Cytokine Quantitation BioLegend's ELISA Max™ Sets provide all the time-savings, convenience and performance of a high-end, commercial ELISA kit for a fraction of the price! BioLegend's ELISA Max™ Sets, in two appealing formats, address the need for sensitivity, accuracy, dependability, and versatility of an ELISA development system, while providing maximum cost effectiveness, value, and ease of use. Both the ELISA Max™ Set Standard and ELISA Max™ Set Deluxe are specifically engineered for accurate recovery and measurement of analytes in complex fluids, such as serum and plasma (as well as activated cell cultures) without any interference by confounding serum factors, such as heterophilic antibody or rheumatoid factor.\u003cbr\u003e\n5plates\u003cbr\u003e\nVerified Reactivity: Mouse\u003cbr\u003e\nStorage \u0026amp; Handling: Store between 2°C and 8°C\u003cbr\u003e\nApplication: ELISA\u003cbr\u003e\nApplication References(PubMed link indicates BioLegend citation): Tallima H, et. al. 2009. Cytokine 48:239. PubMed El Ridi R, et al. 2010. Microbes Infect. epub. PubMed\u003cbr\u003e\nProduct Citations: Yang J, et al. 2023. Vaccines (Basel). 11:. PubMed Wang Z, et al. 2022. Nat Commun. 13:7815. PubMed Mukherjee P, et al. 2022. J Lipid Res. 63:100153. PubMed Xi L, et al. 2022. Acta Pharm Sin B. 12:339. PubMed Kinsella S, et al. 2021. Cell Rep. 37:109789. PubMed He Z, et al. 2021. Cell Metab. 33:1358. PubMed Zeng Q, et al. 2022. iScience. 25:105151. PubMed Pan Y, et al. 2021. Br J Pharmacol. 178:4907. PubMed Moreno-Fernandez ME, et al. 2021. Cell Metab. 33:1187. PubMed\u003cbr\u003e\nSensitivity: 8 pg\/mL\u003cbr\u003e\nStandard Range: 15.6-1,000 pg\/mL\u003cbr\u003e\nCell Sources: Dendritic cells, monocytes\/macrophages, B cells, T cells\u003cbr\u003e\nBiology Area: Immunology, Innate Immunity\u003cbr\u003e\nMolecular Family: Cytokines\/Chemokines\u003cbr\u003e\nGene ID: 1616083430\u003cbr\u003e\nUniProt: View information about IL-23 on UniProt.org\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: IL-23 (p19\/p40) ELISA kit, IL23 (p19\/p40) ELISA kit\u003cbr\u003e\nQ: Do the ELISA MAX™ Deluxe Sets come with plates?\u003cbr\u003e\nA: No, ELISA MAX™ Deluxe Sets do not come with plates. Coating Buffer and Assay Diluent (for blocking and dilutions) are included in these sets. Plates can be ordered separately (Cat No. 423501), and instructions for coating the plates are in the sets’ product manuals.\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46864239558825,"sku":"433704","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/biolegend-433704","provider":"Iright","version":"1.0","type":"link"}