{"product_id":"biolegend-544001","title":"Biolegend, 544001, Purified anti-ICAM-2 Antibody, 50microl","description":"\u003cp\u003eIntracellular adhesion molecule 2 (ICAM2) is a type I transmembrane glycoprotein that mediates cell-cell adhesions. Specifically, ICAM2 binds to LFA-1, a member of the integrin family primarily expressed by lymphocytes. ICAM2 expression regulates the migration of leukocytes and neutrophils via cell-cell interactions and plays an important role in their development and immune response. Additionally, ICAM2 controls the adhesion of developing sperm in the testis and is important for proper spermatogenesis.\u003cbr\u003e\n50microl\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nAntibody Type: Polyclonal\u003cbr\u003e\nHost Species: Goat\u003cbr\u003e\nImmunogen: Recombinant fragment of human ICAM-2\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography.\u003cbr\u003e\nConcentration: Lot-specific (to obtain lot-specific concentration and expiration, please enter the lot number in our Certificate of Analysis online tool.)\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C.\u003cbr\u003e\nApplication: WB - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by western blotting. For western blotting, the suggested use of this reagent is 0.25 - 1.0 µg\/mL. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nApplication Notes: This product is not suitable for IHC-P. This product does not cross-react with human ICAM-1 in Western Blot.\u003cbr\u003e\nRRID: AB_2941599 (BioLegend Cat. No. 544001)\u003cbr\u003e\nStructure: ICAM-2 is a 275 amino acid protein with an estimated molecular weight of 30.6 kD.\u003cbr\u003e\nDistribution: Plasma membrane, cytosol\u003cbr\u003e\nFunction: Cell-cell adhesion\u003cbr\u003e\nLigand\/Receptor: Lymphocyte function-associated antigen 1 (LFA-1)\u003cbr\u003e\nBiology Area: Cell Adhesion, Cell Biology, Immunology\u003cbr\u003e\nMolecular Family: CD Molecules\u003cbr\u003e\nAntigen References: Xiao X, et al. 2013. Hum Reprod Update. 19:167-86. Lyck R, et al. 2015. Curr Opin Hematol. 22:53-9. Gahmberg CG, et al. 1998. Cell Mol Life Sci. 54:549-55.\u003cbr\u003e\nGene ID: 3384\u003cbr\u003e\nUniProt: View information about ICAM-2 on UniProt.org\u003cbr\u003e\nClone: Poly5440\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: Intracellular adhesion molecule 2 (ICAM2), Cluster of Differentiation 102 (CD102)\u003cbr\u003e\nIsotype: Goat Polyclonal IgG\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866167562409,"sku":"544001","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/biolegend-544001","provider":"Iright","version":"1.0","type":"link"}