{"product_id":"biolegend-612002","title":"Biolegend, 612002, Purified anti-FOXA1 Antibody, 100μg","description":"\u003cp\u003eFOXA1 is a transcriptional activator that is required for tissue-specific differentiation during embryonic development. It also functions as a coactivator with nuclear hormone receptors, including ESR1, and has been shown to play a major role in driving estrogen receptor positive breast cancers.\u003cbr\u003e\n100μg\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nImmunogen: Full length recombinant human FOXA1\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography.\u003cbr\u003e\nConcentration: 0.5 mg\/ml\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C.\u003cbr\u003e\nApplication: WB - Quality tested ICC, IHC-P - Verified\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.1 - 1.0 µg per ml. For immunocytochemistry, a concentration range of 1.25 - 5.0 μg\/ml is recommended. For immunohistochemistry on formalin-fixed paraffin-embedded tissue sections, a concentration range of 5.0 - 10 µg\/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nApplication Notes: When using this clone for western blot, we highly recommend using lysate that has not been subjected to any freeze-thaw cycles.\u003cbr\u003e\nApplication References(PubMed link indicates BioLegend citation): Besenard V, et al. 2004. Gene Expr Patterns. 5:193-208. (IHC-P)\u003cbr\u003e\nRRID: AB_2801115 (BioLegend Cat. No. 612001) AB_2801116 (BioLegend Cat. No. 612002)\u003cbr\u003e\nStructure: FOXA1 is a 472 amino acid protein with a predicted molecular weight of 49 kD.\u003cbr\u003e\nDistribution: Nucleus\/Early endoderm derived cells\u003cbr\u003e\nFunction: Transcriptional activator\u003cbr\u003e\nInteraction: FOXA2, NKX2-1, Histones H3 and H4\u003cbr\u003e\nBiology Area: Cell Biology, Transcription Factors\u003cbr\u003e\nMolecular Family: Nuclear Markers\u003cbr\u003e\nGene ID: 3169\u003cbr\u003e\nUniProt: View information about FOXA1 on UniProt.org\u003cbr\u003e\nClone: 2F83\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: Forkhead box protein A1, HNF3α, Hepatic nuclear factor 3 α\u003cbr\u003e\nIsotype: Mouse IgG1, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46862325940393,"sku":"612002","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/biolegend-612002","provider":"Iright","version":"1.0","type":"link"}