{"product_id":"biolegend-663104","title":"Biolegend, 663104, Purified anti-, 100μg","description":"\u003cp\u003eDNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit plays an important role in subunit assembly since its dimerization is the first step in the sequential assembly of subunits to form the holoenzyme.\u003cbr\u003e\n100μg\u003cbr\u003e\nVerified Reactivity: E. coli\u003cbr\u003e\nReported Reactivity: Other species\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography.\u003cbr\u003e\nConcentration: 0.5 mg\/ml\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C.\u003cbr\u003e\nApplication: WB - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.1-1.0 ug\/mL (1:500-1:5000). It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nApplication References(PubMed link indicates BioLegend citation): Lesley SA and Burgess RR. 1989. Biochemistry 28:7728.\u003cbr\u003e\nProduct Citations: Chang S, et al. 2022. Nat Struct Mol Biol. 29:932. PubMed Gibson JA, et al. 2022. Proc Natl Acad Sci U S A. 119:e2210115119. PubMed Hummels KR, et al. 2023. Nature. 615:300. PubMed Sanderlin AG, et al. 2022. J Bacteriol. 204:e0018222. PubMed Prentice JA, et al. 2022. J Bacteriol. 204:e0024922. PubMed Liang Q, et al. 2022. Front Cell Infect Microbiol. 12:1081614. PubMed Park SY, et al. 2022. Cell. 185:513. PubMed Di Venanzio G, et al. 2019. Nat Commun. 10:2763. PubMed Hernandez–Doria JD, et al. 2018. Cell Host Microbe. 23:607. PubMed Shin JH, et al. 2021. EMBO Rep. 22:e51790. PubMed Tomasek D, et al. 2020. Nature. 583:473. PubMed Han K, et al. 2021. MBio. 12:. PubMed Shin JH, et al. 2020. Biochem Biophys Res Commun. 528:493. PubMed Guo MS et al. 2018. Cell. 175(2):583-597 . PubMed Martin NR, et al. 2021. Nat Microbiol. 6:910. PubMed Weaver AI, et al. 2022. Elife. 11:. PubMed Zingl FG, et al. 2020. Cell Host \u0026amp; Microbe. 27(2):225-237.e8.. PubMed Bridges AA, et al. 2021. Elife. 10:. PubMed Yang N, et al. 2020. Mol Microbiol. 114:423. PubMed Guzzo M, et al. 2021. Dev Cell. 56:2145. PubMed\u003cbr\u003e\nRRID: AB_2687386 (BioLegend Cat. No. 663104)\u003cbr\u003e\nStructure: α is a 36 kD subunit of the E. coli RNA polymerase.\u003cbr\u003e\nBiology Area: Cell Biology, Transcription Factors\u003cbr\u003e\nMolecular Family: Nuclear Markers\u003cbr\u003e\nGene ID: 947794\u003cbr\u003e\nUniProt: View information about RNA Polymerase alpha on UniProt.org\u003cbr\u003e\nClone: 4RA2\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: RNA polymerase subunit alpha, Transcriptase subunit alpha, pez, phs, sez\u003cbr\u003e\nIsotype: Mouse IgG1\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46862419198121,"sku":"663104","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/biolegend-663104","provider":"Iright","version":"1.0","type":"link"}