{"product_id":"biolegend-820901","title":"Biolegend, 820901, Purified anti-PME-1 Antibody (Previously Covance catalog# MMS-5239), 100microl","description":"\u003cp\u003eProtein phosphatase methylesterase-1 (PME-1) is an enzyme that catalyzes the demethylation and inactivation of protein phosphatase (PP2A). PP2A is a heterotrimeric serine\/threonine phosphatase that regulates proteins of oncogenic signaling pathways such as Raf, MEK and Akt. PP2A is associated with growth inhibition and cell cycle arrest.\u003cbr\u003e\n100microl\u003cbr\u003e\nVerified Reactivity: Human, Mouse, Rat\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nImmunogen: This monoclonal antibody was raised against a HIS-tagged, full-length mouse PME1 protein.\u003cbr\u003e\nFormulation: Phosphate-buffered solution.\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography.\u003cbr\u003e\nConcentration: 1 mg\/ml\u003cbr\u003e\nStorage \u0026amp; Handling: This antibody should be handled aseptically as it is free of preservatives such as Sodium Azide. Store this antibody undiluted between 2°C and 8°C. Please note the storage condition for this antibody has been changed from -20°C to between 2°C and 8°C. You can also check the vial label or CoA to find the proper storage conditions.\u003cbr\u003e\nApplication: WB - Quality tested IHC-P, KO\/KD-WB - Verified\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.5 - 10 µg per ml. For immunohistochemistry, a concentration of 10 µg\/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nApplication Notes: This antibody is effective in immunoblotting (WB) and immunohistochemistry on formalin-fixed paraffin-embedded tissue (IHC-P).\u003cbr\u003e\nRRID: AB_2564845 (BioLegend Cat. No. 820901)\u003cbr\u003e\nStructure: Expected MW: 42 kD\u003cbr\u003e\nBiology Area: Cell Biology, Neurodegeneration, Neuroscience, Protein Misfolding and Aggregation\u003cbr\u003e\nMolecular Family: Protein Kinases\/Phosphatase\u003cbr\u003e\nGene ID: 51400\u003cbr\u003e\nUniProt: View information about PME-1 on UniProt.org\u003cbr\u003e\nClone: 8A6-F8\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: Protein phosphatase methylesterase 1, protein phosphatase methylesterase-1, PME1\u003cbr\u003e\nPreviously: Covance Catalog# MMS-5239\u003cbr\u003e\nIsotype: Mouse IgG1, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46862492631209,"sku":"820901","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/biolegend-820901","provider":"Iright","version":"1.0","type":"link"}