{"product_id":"biolegend-858601","title":"Biolegend, 858601, Purified anti-CD133 (Prominin-1) Antibody, 25μg","description":"\u003cp\u003eProminin-1 (Prom1), also known as CD133, is a transmembrane glycoprotein located mainly on cellular protrusions of neurons and glial stem cells in the nervous system. CD133 level has been used as marker for isolation of cancer stem cells from various gliomas. Prom1 is also expressed in other tissues including kidney, mammary glands, and uterus.\u003cbr\u003e\n25μg\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography.\u003cbr\u003e\nConcentration: 0.5 mg\/ml\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C.\u003cbr\u003e\nApplication: WB - Quality tested\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 5.0 - 10 µg per ml. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nRRID: AB_2801221 (BioLegend Cat. No. 858601) AB_2801222 (BioLegend Cat. No. 858602)\u003cbr\u003e\nStructure: Prom1 is an 865 amino acid protein with an apparent molecular mass of ~ 97 kD.\u003cbr\u003e\nDistribution: Cellular Distribution: Plasma membrane, extracellular, and endoplasmic reticulum. Tissue Distribution: Glioblastomas; liver,gallbladder, cervix, uterus, and endometrium.\u003cbr\u003e\nFunction: Used as a marker for isolation of cancer stem cells.\u003cbr\u003e\nInteraction: CDHR1, Actin, NAT8, NAT8B\u003cbr\u003e\nCell Type: Neural Stem Cells, Neurons\u003cbr\u003e\nBiology Area: Immuno-Oncology, Neuroscience\u003cbr\u003e\nMolecular Family: CD Molecules\u003cbr\u003e\nAntigen References: Nagare RP, et al. 2017. Curr Stem Cell Res Ther. 12(1):37 Dahlrot RH, et al. 2013. Int J Clin Exp Pathol. 6(3):334 Donovan LK, et al. 2012. Cell Prolif. 45(6):527\u003cbr\u003e\nGene ID: 8842\u003cbr\u003e\nUniProt: View information about CD133 on UniProt.org\u003cbr\u003e\nClone: 8F2-H6-D6\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: Prom1, Prominin-1, CD133\u003cbr\u003e\nIsotype: Mouse IgG2a, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46862495449257,"sku":"858601","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/biolegend-858601","provider":"Iright","version":"1.0","type":"link"}