{"product_id":"biolegend-868701","title":"Biolegend, 868701, Purified anti-CKMT2 Antibody, 25μg","description":"\u003cp\u003eCKMT2 is an isoform of the mitochondrial specific creatine kinase subunit that is mainly expressed in skeletal and heart muscle cells. CKMT2 exists in two different oligomeric forms: dimers and octamers. Recent studies have shown that the homooctameric form of CKMT2 is the predominant form in vivo and is critical to its function.\u003cbr\u003e\n25μg\u003cbr\u003e\nVerified Reactivity: Human, Mouse, Rat\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography.\u003cbr\u003e\nConcentration: 0.5 mg\/ml\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C.\u003cbr\u003e\nApplication: WB - Quality testedIHC-P, ICC - Verified\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.5 - 10 µg per mL. For immunohistochemistry on formalin-fixed paraffin-embedded tissue sections, a concentration range of 0.5 - 10 µg\/mL is suggested. For immunocytochemistry, a concentration of 10 μg\/mL is recommended. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nRRID: AB_2814623 (BioLegend Cat. No. 868701) AB_2814624 (BioLegend Cat. No. 868702)\u003cbr\u003e\nStructure: CKMT2 is a 419 amino acid protein with predicted and observed molecular mass of ~47 kD.\u003cbr\u003e\nDistribution: Tissue Distribution: Mainly expressed in heart and skeletal muscle. Also expressed in brain. Cellular Distribution: Mitochondrion and cytosol\u003cbr\u003e\nFunction: CKMT2 plays a central role in energy transduction in tissues with large, fluctuating energy demands such as the brain.\u003cbr\u003e\nInteraction: CKMT2 exists as octamer composed of four homodimers.\u003cbr\u003e\nBiology Area: Mitochondrial Function, Neurodegeneration, Neuroscience\u003cbr\u003e\nMolecular Family: Mitochondrial Markers\u003cbr\u003e\nAntigen References: Zervou S, et al. 2017. PLoS One. 12(8):e0182994 Forsey KE, et al. 2013. Mol Reprod Dev. 80(3):185 Miceli MV, et al. 2005. Exp Cell Res. 302 (2):270\u003cbr\u003e\nGene ID: 116076722688698\u003cbr\u003e\nUniProt: View information about CKMT2 on UniProt.org\u003cbr\u003e\nClone: 3F4-G5-H5\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: Creatine Kinase, Mitochondrial 2\u003cbr\u003e\nIsotype: Mouse IgG2b, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46862395900073,"sku":"868701","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/biolegend-868701","provider":"Iright","version":"1.0","type":"link"}