{"product_id":"biolegend-916504","title":"Biolegend, 916504, Purified anti-Cytokeratin, HMW Antibody, 100μg","description":"\u003cp\u003eThis antibody is specific for high molecular weight cytokeratins 1, 5, 10 and 14. Clone 34βE12 is immunoreactive with squamous and adeno-squamous carcinomas. In normal epithelia, the antibody stains stratified epithelia, myoepithelial cells and basal cells in the prostate gland and bronchi. This antibody is also useful in differentiating benign and malignant tumors of the prostate gland.\u003cbr\u003e\n100μg\u003cbr\u003e\nVerified Reactivity: Human\u003cbr\u003e\nAntibody Type: Monoclonal\u003cbr\u003e\nHost Species: Mouse\u003cbr\u003e\nImmunogen: This antibody was developed using a solubilized keratin extracted from human stratum corneum.\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography.\u003cbr\u003e\nConcentration: 0.5 mg\/ml\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C.\u003cbr\u003e\nApplication: IHC-P - Quality testedWB - Verified\u003cbr\u003e\nRecommended Usage: Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration range of 0.5 - 5.0 μg\/ml is suggested. For Western blotting, a concentration range of 1.0 - 10 μg\/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application.\u003cbr\u003e\nApplication Notes: The Cytokeratin, High Molecular Weight (HMW) antibody (clone 34ßE12) reacts primarily with complex epithelium such as squamous, ductal and transitional epithelium and corresponding tumors.\u003cbr\u003e\nApplication References(PubMed link indicates BioLegend citation): Gown AM, Vogel AM. 1985. Am. J. Clin. Pathol. 84:413. (IHC) Gown AM, Vogel AM. 1982. J. Cell Biol. 95:414. (IHC)\u003cbr\u003e\nRRID: AB_2629548 (BioLegend Cat. No. 916504)\u003cbr\u003e\nDistribution: Tissue distribution: skin, prostate or squamous cell carcinoma. Cellular distribution: cytoplasm.\u003cbr\u003e\nBiology Area: Cell Biology, Cell Motility\/Cytoskeleton\/Structure, Neuroscience, Neuroscience Cell Markers\u003cbr\u003e\nMolecular Family: Intermediate Filaments\u003cbr\u003e\nGene ID: NA\u003cbr\u003e\nUniProt: View information about Cytokeratin on UniProt.org\u003cbr\u003e\nClone: 34βE12\u003cbr\u003e\nRegulatory Status: RUO\u003cbr\u003e\nOther Names: Cytokeratin, high-molecular weight keratin (HMWK), high-molecular weight cytokeratin (HMWCK)\u003cbr\u003e\nIsotype: Mouse IgG1, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46862379450537,"sku":"916504","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/biolegend-916504","provider":"Iright","version":"1.0","type":"link"}