{"product_id":"biolegend-986010","title":"Biolegend, 986010, APC anti-human CD127, 500microl","description":"\u003cp\u003eCD127 is a 60-90 kD type I transmembrane glycoprotein also known as IL-7 receptor α chain or IL-7Rα. It forms a heterodimer with the common γ chain (γc or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage cells, thymocytes (except CD4\/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be a useful marker for identifying memory and effector T cells. Studies have shown that CD127 expression is down-modulated on Treg cells. It can be used as a marker for differentiation of Treg and conventional T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cell proliferation and development.\u003cbr\u003e\n500microl\u003cbr\u003e\nReactivity: Human\u003cbr\u003e\nFormulation: Phosphate-buffered solution, pH7.2, 0.09% sodium azide, 0.2% (w\/v) BSA (origin USA), and a stabilizer.\u003cbr\u003e\nPreparation: The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions.\u003cbr\u003e\nConcentration: 50 µg\/mL\u003cbr\u003e\nStorage \u0026amp; Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.\u003cbr\u003e\nApplication: Suggested for Flow Cytometry\u003cbr\u003e\nDisclaimer: WARNINGS AND PRECAUTIONS Use appropriate personal protective equipment and safety practices per universal precautions when working with this reagent. Refer to the reagent safety data sheet. This antibody contains sodium azide. Follow federal, state and local regulations to dispose of this reagent. Sodium azide build-up in metal wastepipes may lead to explosive conditions; if disposing of reagent down wastepipes, flush with water after disposal. All specimens, samples and any material coming in contact with them should be considered potentially infectious and should be disposed of with proper precautions and in accordance with federal, state and local regulations. Do not use this reagent beyond the expiration date stated on the label. Do not use this reagent if it appears cloudy or if there is any change in the appearance of the reagent as these may be an indication of possible deterioration. Avoid prolonged exposure of the reagent or stained cells to light.\u003cbr\u003e\nAntigen References: Sudo T, et al. 1993. P. Natl. Acad. Sci. USA. 90:9125. He YW and Malek TR. 1998. Crit. Rev. Immunol. 18:503. Huster KM, et al. 2004. P. Natl. Acad. Sci. USA. 101:5610. Pillai M, et al. 2004. Leukemia Lymphoma. 45:2403. Morrissey PJ, et al. 1989. J. Exp. Med. 169:707. Liu W, et al. 2006. J. Exp. Med. 203:1701.\u003cbr\u003e\nClone: A019D5\u003cbr\u003e\nOther Names: IL-7 receptor α chain, IL-7Rα\u003cbr\u003e\nIsotype: Mouse IgG1, κ\u003c\/p\u003e","brand":"Biolegend","offers":[{"title":"Default Title","offer_id":46866571264169,"sku":"986010","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/biolegend-986010","provider":"Iright","version":"1.0","type":"link"}