{"product_id":"proteintech-10496-1-ap","title":"Proteintech, 10496-1-AP, HOXD3 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe HOXD3 (10496-1-AP) by Proteintech is a Polyclonal antibody targeting HOXD3 in IHC, IF\/ICC, ELISA applications with reactivity to human, mouse samples\n10496-1-AP targets HOXD3 in IHC, IF\/ICC, ELISA applications and shows reactivity with human, mouse samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive IHC detected in: mouse testis tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0\nPositive IF\/ICC detected in: U2OS cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nImmunohistochemistry (IHC): IHC : 1:50-1:500\nImmunofluorescence (IF)\/ICC: IF\/ICC : 1:200-1:800\n\u003cb\u003eBackground Information\u003c\/b\u003e\nHomeobox D3 (HOXD3),  a member of the Homeobox (Hox) family of master transcription factors, is a homeobox transcription factor that promotes angiogenesis and collagen synthesis. HOXD3 is expressed during normal embryogenesis, skin development, and fetal wound healing (PMID: 14633614). The overexpression of  HOXD3 plays a critical role in breast cancer stemness and drug resistance via integrin β3-mediated Wnt\/β-catenin signaling (PMID: 29698974).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag0768 Product name: Recombinant human HOXD3 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-200 aa of BC005124 Sequence: MLFEQGQQALELPECTMQKAAYYENPGLFGGYGYSKTTDTYGYSTPHQPYPPPAAASSLDTDYPGSACSIQSSAPLRAPAHKGAELNGSCMRPGTGNSQGGGGGSQPPGLNSEQQPPQPPPPPPTLPPSSPTNPGGGVPAKKPKGGPNASSSSATISKQIFPWMKESRQNSKQKNSCATAGESCEDKSPPGPASKRVRTA Predict reactive species\nFull Name: homeobox D3\nCalculated Molecular Weight: 46 kDa\nGenBank Accession Number: BC005124\nGene Symbol: HOXD3\nGene ID (NCBI): 3232\nRRID: AB_2233224\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: P31249\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887670808745,"sku":"10496-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-10496-1-ap","provider":"Iright","version":"1.0","type":"link"}