{"product_id":"proteintech-10500-1-ap","title":"Proteintech, 10500-1-AP, ASC\/TMS1 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe ASC\/TMS1 (10500-1-AP) by Proteintech is a Polyclonal antibody targeting ASC\/TMS1 in WB, IHC, IP, ELISA applications with reactivity to human samples\n10500-1-AP targets ASC\/TMS1 in WB, IHC, IF, IP, CoIP, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: HL-60 cells, A549 cells,  Raji cells,  U-937 cells,  THP-1 cells\nPositive IP detected in: HL-60 cells\nPositive IHC detected in: human lung cancer tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:5000-1:50000\nImmunoprecipitation (IP): IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate\nImmunohistochemistry (IHC): IHC : 1:200-1:1000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nPYCARD , also known as ASC or TMS1, is a 195 amino acid protein containing an N-terminal Pyrin-like domain (PYD) and an 87 residue C-terminal Caspase-associated recruitment domain (CARD). It promotes caspase-mediated apoptosis which is mediated predominantly through the activation of caspase-9.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nCited Reactivity: human, pig, canine, bovine\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag0774 Product name: Recombinant human TMS1 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-135 aa of BC004470 Sequence: MGRARDAILDALENLTAEELKKFKLQAATHQGSGAAPAGIQAPPQSAAKPGLHFIDQHRAALIARVTNVEWLLDALYGKVLTDEQYQAVRAEPTNPSKMRKLFSFTPAWNWTCKDLLLQALRESQSYLVEDLERS Predict reactive species\nFull Name: PYD and CARD domain containing\nCalculated Molecular Weight: 25 kDa\nObserved Molecular Weight: 22-25 kDa\nGenBank Accession Number: BC004470\nGene Symbol: ASC\/TMS1\nGene ID (NCBI): 29108\nRRID: AB_2174862\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q9ULZ3\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46868821344425,"sku":"10500-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-10500-1-ap","provider":"Iright","version":"1.0","type":"link"}