{"product_id":"proteintech-11948-1-ap","title":"Proteintech, 11948-1-AP, DOK5 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe DOK5 (11948-1-AP) by Proteintech is a Polyclonal antibody targeting DOK5 in WB, ELISA applications with reactivity to human, mouse, rat samples\n11948-1-AP targets DOK5 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: mouse liver tissue\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:2000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nDOK5 belongs to the docking family of proteins that contain tandem pleckstrin homology-phosphotyrosine binding (PH-PTB) domains at their amino termini (PMID: 19909370). DOK proteins are also known as INS receptor substrates (IRS) and serve as substrates for INS and INS-like growth factor (PMID: 12730241 ) as well as various protein tyrosine kinases (PMID: 16647839). DOK5 functions as a specific signal transduction molecule and plays an important role in cellular differentiation. DOK5 is upregulated in systemic Sclerosis and Associated with IGFBP-5-Induced fibrosis (PMID: 24551065).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse, rat\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag2615 Product name: Recombinant human DOK5 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-198 aa of BC008992 Sequence: MECVGTRINDISLGEPDLLATGVEREQSERFNVYLMPSPNLDVHGECALQITYEYICLWDVQNPRVKLISWPLSALRRYGRDTTWFTFEAGRMCETGEGLFIFQTRDGEAIYQKVHSAALAIAEQHERLLQSVKNSMLQMKMSERAASLSTMVPLPRSAYWQHITRQHSTGQLYRLQDVSSPLKLHRTETFPAYRSEH Predict reactive species\nFull Name: docking protein 5\nCalculated Molecular Weight: 306 aa, 35 kDa\nObserved Molecular Weight: 35 kDa\nGenBank Accession Number: BC008992\nGene Symbol: DOK5\nGene ID (NCBI): 55816\nRRID: AB_10665550\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q9P104\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887292797097,"sku":"11948-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-11948-1-ap","provider":"Iright","version":"1.0","type":"link"}