{"product_id":"proteintech-12286-1-ap","title":"Proteintech, 12286-1-AP, CYP4F11 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe CYP4F11 (12286-1-AP) by Proteintech is a Polyclonal antibody targeting CYP4F11 in WB, IHC, IF\/ICC, ELISA applications with reactivity to human samples\n12286-1-AP targets CYP4F11 in WB, IHC, IF\/ICC, ChIP, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: A549 cells, human liver tissue,  human kidney tissue,  MCF-7 cells,  mouse liver tissue\nPositive IHC detected in: human liver cancer tissue, human bowen diseaseNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0\nPositive IF\/ICC detected in: A549 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:1000-1:6000\nImmunohistochemistry (IHC): IHC : 1:200-1:800\nImmunofluorescence (IF)\/ICC: IF\/ICC : 1:200-1:800\n\u003cb\u003eBackground Information\u003c\/b\u003e\nCYP4F11, also named as CYPIVF11, belongs to the cytochrome P450 family. It is the lone CYP4F\/A enzyme that effectively oxidized 3-hydroxypalmitate. It is the predominant catalyst of this fatty acid oxidation reaction in human liver. CYP4F11 is one of the primary human epidermal keratinocytes. It is positively regulated by multiple signaling pathways in HaCaT keratinocytes, including RXR and JNK signaling pathways. (PMID:19812349)\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nCited Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag2906 Product name: Recombinant human CYP4F11 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 175-524 aa of BC016853 Sequence: HDKWQRLASEGSARLDMFEHISLMTLDSLQKCVFSFESNCQEKPSEYIAAILELSAFVEKRNQQILLHTDFLYYLTPDGQRFRRACHLVHDFTDAVIQERRRTLPTQGIDDFLKNKAKSKTLDFIDVLLLSKDEDGKELSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQCRQEVQELLKDREPIEIEWDDLAQLPFLTMCIKESLRLHPPVPVISRCCTQDFVLPDGRVIPKGIVCLINIIGIHYNPTVWPDPEVYDPFRFNQENIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALTLLHFRILPTHTEPRRKPELILRAEGGLWLRVEPLGANSQ Predict reactive species\nFull Name: cytochrome P450, family 4, subfamily F, polypeptide 11\nCalculated Molecular Weight: 524 aa, 60 kDa\nObserved Molecular Weight: 57 kDa\nGenBank Accession Number: BC016853\nGene Symbol: CYP4F11\nGene ID (NCBI): 57834\nRRID: AB_2088407\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q9HBI6\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46869455470761,"sku":"12286-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-12286-1-ap","provider":"Iright","version":"1.0","type":"link"}