{"product_id":"proteintech-12349-1-ap","title":"Proteintech, 12349-1-AP, QTRT1 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe QTRT1 (12349-1-AP) by Proteintech is a Polyclonal antibody targeting QTRT1 in WB, ELISA applications with reactivity to human samples\n12349-1-AP targets QTRT1 in WB, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: HeLa cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:2000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nQTRT1 (Queuine tRNA-ribosyltransferase catalytic subunit 1), also known as tRNA-guanine transglycosylase (TGT), is a key enzymeinvolved in the post-transcriptional modification of tRNAs. In humans, the QTRT1 and QTRT2 heterodimer complex exhibits transglycosylase activity, and replaces the guanine base of the first letter of the tRNA anticodon with q, thus forming Q on the tRNA (PMID: 30149595, 25884661). High QTRT1 expression is a biomarkerfor poor prognosis in LUAD patients, and QTRT1 mayfunction as a latent tumor biomarker in the prognosticprediction for LUAD (PMID: 33490170).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag3010 Product name: Recombinant human QTRT1 protein Source: e coli. -derived, T-HIS Tag: 6*His Domain: 1-358 aa of BC015350 Sequence: MPVGTQATMKGITTEQLDALGCRICLGNTYHLGLRPGPELIQKANGLHGFMNWPHNLLTDSGGFQMVSLVSLSEVTEEGVRFRSPYDGNETLLSPEKSVQIQNALGSDIIMQLDDVVSSTVTGPRVEEAMYRSIRWLDRCIAAHQRPDKQNLFAIIQGGLDADLRATCLEEMTKRDVPGFAIGGLSGGESKSQFWRMVALSTSRLPKDKPRYLMGVGYATDLVVCVALGCDMFDCVFPTRTARFGSALVPTGNLQLRKKVFEKDFGPIDPECTCPTCQKHSRAFLHALLHSDNTAALHHLTVHNIAYQLQLMSAVRTSIVEKRFPDFVRDFMGAMYGDPTLCPTWATDALASVGITLG Predict reactive species\nFull Name: queuine tRNA-ribosyltransferase 1\nCalculated Molecular Weight: 403 aa, 44 kDa\nObserved Molecular Weight: 44 kDa\nGenBank Accession Number: BC015350\nGene Symbol: QTRT1\nGene ID (NCBI): 81890\nRRID: AB_2877847\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q9BXR0\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887778058409,"sku":"12349-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-12349-1-ap","provider":"Iright","version":"1.0","type":"link"}