{"product_id":"proteintech-13140-1-ap","title":"Proteintech, 13140-1-AP, RDH5 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe RDH5 (13140-1-AP) by Proteintech is a Polyclonal antibody targeting RDH5 in WB, ELISA applications with reactivity to human, mouse, rat samples\n13140-1-AP targets RDH5 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: mouse eye tissue, rat eye tissue\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:1000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nRDH5, also named as RDH1, SDR9C5 and HSD17B9, belongs to short-chain dehydrogenases\/reductases (SDR) family. RDH5 catalyzes the oxidation of cis-isomers of retinol in an NAD-dependent manner for the final step in the biosynthesis of 11-cis retinaldehyde. Mutations in this gene are associated with fundus albipunctatus, an autosomal recessive eye disease characterized by stationary night blindness and accumulation of white spots in the retina (PubMed:11675386). The predicted size of this protein is 35 kDa. Some paper have reported that the molecular weight is 32 kDa and could form a dimer of about 60 kDa.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse, rat\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag3784 Product name: Recombinant human RDH5 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 19-290 aa of BC028298 Sequence: RDRQSLPASNALVFITGCDSGFGRLLALQLDQRGFRVLASCLTPSGAEDLQRVASSRLHTTLLDITDPQSVQQAAKWVEMHVKEAGLFGLVNNAGVAGIIGPTPWLTRDDFQRVLNVNTMGPIGVTLALLPLLQQARGRVINITSVLGRLAANGGGYCVSKFGLEAFSDSLRRDVAHFGIRVSIVEPGFFRTPVTNLESLEKTLQACWARLPPATQAHYGGAFLTKYLKMQQRIMNLICDPDLTKVSRCLEHALTARHPRTRYSPGWDAKLL Predict reactive species\nFull Name: retinol dehydrogenase 5 (11-cis\/9-cis)\nCalculated Molecular Weight: 318 aa, 35 kDa\nObserved Molecular Weight: 32 kDa\nGenBank Accession Number: BC028298\nGene Symbol: RDH5\nGene ID (NCBI): 5959\nRRID: AB_2918031\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q92781\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887781761193,"sku":"13140-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-13140-1-ap","provider":"Iright","version":"1.0","type":"link"}