{"product_id":"proteintech-13871-1-ap","title":"Proteintech, 13871-1-AP, KBTBD2 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe KBTBD2 (13871-1-AP) by Proteintech is a Polyclonal antibody targeting KBTBD2 in WB, ELISA applications with reactivity to human, mouse, rat samples\n13871-1-AP targets KBTBD2 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: COLO 320 cells, A549 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:1000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nKelch repeat and BTB domain containing 2(KBTBD2), also known as BTB and kelch domain-containing protein 1, encodes a BTB-Kelch family subunit that p85α-specific recognition for the Cullin3-based E3 ubiqitin ligase complex, which regulates p85α protein ubiquitination and subsequently regulates phosphoinositide-3 kinases (PI3K) signaling (PMID:27708159). However, the expression profile and functional significance of Kbtbd2 is still largely unknown. The Human Protein Atlas which is an online source shows high Kbtbd2 expression in the spleen and thymus, suggesting that Kbtbd2 might involved in immunization (PMID:29331106). In addition, Kbtbd2 is related to Src-induced phosphorylation of protein, spermatogonial stem cell activity(PMID:15623525, 29331106). \nA 60-70 kDa band has also been reported(PMID:27708159).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse, rat\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag4823 Product name: Recombinant human KBTBD2 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-349 aa of BC047107 Sequence: MSTQDERQINTEYAVSLLEQLKLFYEQQLFTDIVLIVEGTEFPCHKMVLATCSSYFRAMFMSGLSESKQTHVHLRNVDAATLQIIITYAYTGNLAMNDSTVEQLYETACFLQVEDVLQRCREYLIKKINAENCVRLLSFADLFSCEELKQSAKRMVEHKFTAVYHQDAFMQLSHDLLIDILSSDNLNVGKEETVREAAMLWLEYNTESRSQYLSSVLSQIRIDALSEVTQRAWFQGLPPNDKSVVVQGLYKSMRKFFKPRLGMTKEEMMIFIEASSENPCSLYSSVCYSPQAEKVYKLCSRPADLHKVGTVVTPDNDIYIAGGQVPLKNTKTNHSKTSKLQTAFRTVNC Predict reactive species\nFull Name: kelch repeat and BTB (POZ) domain containing 2\nCalculated Molecular Weight: 622 aa, 71 kDa\nObserved Molecular Weight: 60-70 kDa\nGenBank Accession Number: BC047107\nGene Symbol: KBTBD2\nGene ID (NCBI): 25948\nRRID: AB_2296330\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q8IY47\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887690404009,"sku":"13871-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-13871-1-ap","provider":"Iright","version":"1.0","type":"link"}