{"product_id":"proteintech-14430-1-ap","title":"Proteintech, 14430-1-AP, TSPAN10 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe TSPAN10 (14430-1-AP) by Proteintech is a Polyclonal antibody targeting TSPAN10 in WB, IF\/ICC, ELISA applications with reactivity to human samples\n14430-1-AP targets TSPAN10 in WB, IF\/ICC, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: hTERT-RPE1 cells\nPositive IF\/ICC detected in: hTERT-RPE1 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:2400\nImmunofluorescence (IF)\/ICC: IF\/ICC : 1:20-1:200\n\u003cb\u003eBackground Information\u003c\/b\u003e\nTSPAN10 is a membrane protein of the tetraspanin superfamily, which are characterized by the presence of four conserved transmembrane regions. Tetraspanins have been involved in diverse processes such as cell activation and proliferation, adhesion and motility, differentiation, and cancer. TSPAN10 belongs to the TSPANC8 subfamily, which also include TSPAN5, TSPAN14, TSPAN15, TSPAN17, and TSPAN33. It has been reported that TSPANC8 tetraspanins interact with ADAM10 and have a conserved function in the regulation of ADAM10 trafficking and activity, thereby positively regulating Notch receptor activation (PMID: 23091066; 23035126).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag5807 Product name: Recombinant human TSPAN10 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 181-355 aa of BC032802 Sequence: SLEHTLRVAIAHYQDDPDLRFLLDQVQLGLRCCGAASYQDWQQNLYFNCSSPGVQACSLPASCCIDPREDGASVNDQCGFGVLRLDADAAQRVVYLEGCGPPLRRWLRANLAASGGYAIAVVLLQGAELLLAARLLGALAARSGAAYGPGARGEDRAGPQSPSPGAPPAAKPARG Predict reactive species\nFull Name: tetraspanin 10\nCalculated Molecular Weight: 36.5 kDa\nObserved Molecular Weight: 36-40 kDa\nGenBank Accession Number: BC032802\nGene Symbol: TSPAN10\nGene ID (NCBI): 83882\nRRID: AB_2878057\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q9H1Z9\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887841366185,"sku":"14430-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-14430-1-ap","provider":"Iright","version":"1.0","type":"link"}