{"product_id":"proteintech-14444-1-ap","title":"Proteintech, 14444-1-AP, Phospho-RCC1 (Ser11) Polyclonal antibody","description":"Size: 20ul \/ 100ul\nThe Phospho-RCC1 (Ser11) (14444-1-AP) by Proteintech is a Polyclonal antibody targeting Phospho-RCC1 (Ser11) in WB, ELISA applications with reactivity to human samples\n14444-1-AP targets Phospho-RCC1 (Ser11) in WB, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: A431 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:1000-1:8000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nCHC1, also named as RCC1, promotes the exchange of ran-bound gdp by gtp. It is involved in the regulation of onset of chromosome condensation in the S-phase. Phosphorylation of RCC1 on serines located in or near its nuclear localization signal activates RCC1 to generate RanGTP on mitotic chromosomes, which is required for spindle assembly and chromosome segregation. This antibody is a rabbit polyclonal antibody raised against human phospho-CHC1(Ser11) antigen.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: regulator of chromosome condensation 1\nCalculated Molecular Weight: 48 kDa\nObserved Molecular Weight: 45-50 kDa\nGenBank Accession Number: NM_001048194\nGene Symbol: RCC1\nGene ID (NCBI): 1104\nRRID: AB_2179583\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: P18754\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887761150121,"sku":"14444-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-14444-1-ap","provider":"Iright","version":"1.0","type":"link"}