{"product_id":"proteintech-15642-1-ap","title":"Proteintech, 15642-1-AP, AID Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe AID (15642-1-AP) by Proteintech is a Polyclonal antibody targeting AID in WB, IF-P, ELISA applications with reactivity to human, mouse samples\n15642-1-AP targets AID in WB, IF-P, ELISA applications and shows reactivity with human, mouse samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: MG-63 cells, Ramos cells,  THP-1 cells,  U2OS cells,  NIH\/3T3 cells\nPositive IF-P detected in: human tonsillitis tissue\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:3000\nImmunofluorescence (IF)-P: IF-P : 1:50-1:500\n\u003cb\u003eBackground Information\u003c\/b\u003e\nAID is essential to all three genetic alterations required for antigen-specific immunoglobulin: class switch recombination (CSR), somatic bypermutation (SHM), and gene conversion. Expression of AID is normally restricted to B cells in the GC, where SHM and CSR occur. It is likely these represent AID monomer and homodimer that western blot detected two bands in purified AID from nuclear extracts, one at 52 kDa and the other at 26 kDa. (PMID:16280388)\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag8136 Product name: Recombinant human AID protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-198 aa of BC006296 Sequence: MDSLLMNRRKFLYQFKNVRWAKGRRETYLCYVVKRRDSATSFSLDFGYLRNKNGCHVELLFLRYISDWDLDPGRCYRVTWFTSWSPCYDCARHVADFLRGNPNLSLRIFTARLYFCEDRKAEPEGLRRLHRAGVQIAIMTFKDYFYCWNTFVENHERTFKAWEGLHENSVRLSRQLRRILLPLYEVDDLRDAFRTLGL Predict reactive species\nFull Name: activation-induced cytidine deaminase\nCalculated Molecular Weight: 198 aa, 24 kDa\nObserved Molecular Weight: 24 kDa\nGenBank Accession Number: BC006296\nGene Symbol: AIDA\/AID\nGene ID (NCBI): 57379\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q9GZX7\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46869805793449,"sku":"15642-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-15642-1-ap","provider":"Iright","version":"1.0","type":"link"}