{"product_id":"proteintech-15995-1-ap","title":"Proteintech, 15995-1-AP, PRCP Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe PRCP (15995-1-AP) by Proteintech is a Polyclonal antibody targeting PRCP in WB, IP, IHC, ELISA applications with reactivity to human, mouse samples\n15995-1-AP targets PRCP in WB, IHC, IF, IP, ELISA applications and shows reactivity with human, mouse samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: A549 cells\nPositive IP detected in: L02 cells\nPositive IHC detected in: human lung cancer tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:1000\nImmunoprecipitation (IP): IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate\nImmunohistochemistry (IHC): IHC : 1:50-1:500\n\u003cb\u003eBackground Information\u003c\/b\u003e\nPRCP(Lysosomal Pro-X carboxypeptidase) is also named as PCP and belongs to the peptidase S28 family. This enzyme cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. PRCP is both a PK activator and an angiotensin II inactivator indicates another previously unappreciated interaction between the plasma kallikrein\/kinin and the renin-angiotensin systems(PMID:11830581).Some previous gelfiltration and dynamic-light scattering results suggested that PRCP is a dimer in solution(PMID:20540760). The full length protein has a signal peptide, a propeptide and six glycosylation sites and can exsit as 65 kDa modified protein.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse\nCited Reactivity: human, mouse\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag8869 Product name: Recombinant human PRCP protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 147-496 aa of BC001500 Sequence: SEQALADFAELIKHLKRTIPGAENQPVIAIGGSYGGMLAAWFRMKYPHMVVGALAASAPIWQFEDLVPCGVFMKIVTTDFRKSGPHCSESIHRSWDAINRLSNTGSGLQWLTGALHLCSPLTSQDIQHLKDWISETWVNLAMVDYPYASNFLQPLPAWPIKVVCQYLKNPNVSDSLLLQNIFQALNVYYNYSGQVKCLNISETATSSLGTLGWSYQACTEVVMPFCTNGVDDMFEPHSWNLKELSDDCFQQWGVRPRPSWITTMYGGKNISSHTNIVFSNGELDPWSGGGVTKDITDTLVAVTISEGAHHLDLRTKNALDPMSVLLARSLEVRHMKNWIRDFYDSAGKQH Predict reactive species\nFull Name: prolylcarboxypeptidase (angiotensinase C)\nCalculated Molecular Weight: 496 aa, 56 kDa\nObserved Molecular Weight: 56 kDa\nGenBank Accession Number: BC001500\nGene Symbol: PRCP\nGene ID (NCBI): 5547\nRRID: AB_2169673\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: P42785\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46869490696361,"sku":"15995-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-15995-1-ap","provider":"Iright","version":"1.0","type":"link"}