{"product_id":"proteintech-16770-1-ap","title":"Proteintech, 16770-1-AP, SPAG11A\/B Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe SPAG11A\/B (16770-1-AP) by Proteintech is a Polyclonal antibody targeting SPAG11A\/B in WB, IHC, ELISA applications with reactivity to human samples\n16770-1-AP targets SPAG11A\/B in WB, IHC, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: human testis tissue,  human brain tissue\nPositive IHC detected in: human testis tissue, human kidney tissue,  human placenta tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:2000\nImmunohistochemistry (IHC): IHC : 1:20-1:200\n\u003cb\u003eBackground Information\u003c\/b\u003e\nSperm binding proteins and their C-terminal peptides of the Sperm Associated Antigen 11 (SPAG11) family are found to play an important role in epididymal innate immunity in addition to their role in sperm maturation(PMID:16643671). SPAG11 peptides resulting due to cleavage at the furin-like proprotein convertase motif are reported in the epididymal fluid, ejaculate and on sperm and their antimicrobial activity demonstrated.SPAG11A belongs to this family and is also named as EP2,HE2. It has 4 isoforms produced by alternative splicing. This antibody recognizes SPAG11A and SPAG11B, but not SPAG11, because SPAG11 is a different transcript.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nCited Reactivity: mouse\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag9846 Product name: Recombinant human SPAG11A protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-123 aa of BC058833 Sequence: MRQRLLPSVTSLLLVALLFPGSSQARHVNHSATEALGELRERAPGQGTNGFQLLRHAVKWDLLPPRTPPYQVHISHQEARGPSFKICVGFLGPRWARGCSTGNEKYHLPYAARDLQTFFLPFW Predict reactive species\nFull Name: sperm associated antigen 11A\nCalculated Molecular Weight: 123 aa, 14 kDa\nObserved Molecular Weight: 20 kDa\nGenBank Accession Number: BC058833\nGene Symbol: SPAG11A\nGene ID (NCBI): 653423\nRRID: AB_2286582\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q6PDA7\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46869770469545,"sku":"16770-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-16770-1-ap","provider":"Iright","version":"1.0","type":"link"}