{"product_id":"proteintech-17954-1-ap","title":"Proteintech, 17954-1-AP, HFE Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe HFE (17954-1-AP) by Proteintech is a Polyclonal antibody targeting HFE in WB, ELISA applications with reactivity to human samples\n17954-1-AP targets HFE in WB, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: A549 cells, A375 cells,  Caco-2 cells,  HeLa cells,  HepG2 cells,  human placenta tissue\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:2000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nHFE is an important iron metabolism regulatory protein, which regulates the production of hepcidin through interactions with other proteins such as transferrin receptor 1 (TfR1) and TfR2. HFE is the most common pathogenic gene for hereditary hemochromatosis, which is a hereditary disease of iron accumulation in multiple organs caused by mutations in genes regulating iron metabolism.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag12448 Product name: Recombinant human HFE protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 29-295 aa of BC074721 Sequence: SLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQEGSESSSLPGKVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWE Predict reactive species\nFull Name: hemochromatosis\nCalculated Molecular Weight: 345 aa, 40 kDa\nObserved Molecular Weight: 45-58 kDa\nGenBank Accession Number: BC074721\nGene Symbol: HFE\nGene ID (NCBI): 3077\nRRID: AB_10596779\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q30201\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887667171497,"sku":"17954-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-17954-1-ap","provider":"Iright","version":"1.0","type":"link"}