{"product_id":"proteintech-18191-1-ap","title":"Proteintech, 18191-1-AP, GGTLC2 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe GGTLC2 (18191-1-AP) by Proteintech is a Polyclonal antibody targeting GGTLC2 in WB, ELISA applications with reactivity to human, mouse samples\n18191-1-AP targets GGTLC2 in WB, ELISA applications and shows reactivity with human, mouse samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: 786-O cells, human urine sample,  human milk,  mouse kidney tissue\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:1000-1:6000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nGGT is a protease anchored to the cell membrane, consisting of a light chain and a heavy chain. GGTLC2 (Glutathione hydrolase light chain 2), also known as GGTL4, a constituent of the GGT family, has been characterized as an antioxidant gene, with emerging evidence indicating a potential link between its expression levels and sarcoma patient outcome (PMID: 40191433). Studies have shown that GGTLC2 is highly expressed in gastric cancer, promoting cell proliferation, invasion, and migration while inhibiting apoptosis and ferroptosis.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag12911 Product name: Recombinant human GGTLC2 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-218 aa of BC069534 Sequence: MTSEFFAAQLRAQISDDTTHPISYYKPEFYTPVDGGTAHLSVVAEDGSAVSATSTINLYFGSKVRSPVSGILFNDEMDDFSSPNITNEFGVPPSPANFIQPGKQPLSSMCPTIMVGQDGQPPSHADHTPMPQAIIYNLWFGYDVKRAVEEPRLHNQLLPNVTTVERNIDQAVTAALETRHHHTQIASTFIAVVQAIVRTAGGWAAASDSRKGGEPAGY Predict reactive species\nFull Name: gamma-glutamyltransferase light chain 2\nCalculated Molecular Weight: 218 aa, 24 kDa\nObserved Molecular Weight: 24 kDa\nGenBank Accession Number: BC069534\nGene Symbol: GGTLC2\nGene ID (NCBI): 91227\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q14390\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887650721961,"sku":"18191-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-18191-1-ap","provider":"Iright","version":"1.0","type":"link"}