{"product_id":"proteintech-18251-1-ap","title":"Proteintech, 18251-1-AP, PD-L2\/CD273 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe PD-L2\/CD273 (18251-1-AP) by Proteintech is a Polyclonal antibody targeting PD-L2\/CD273 in WB, ELISA applications with reactivity to human, mouse, rat samples\n18251-1-AP targets PD-L2\/CD273 in WB, IHC, ELISA applications and shows reactivity with human, mouse, rat samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: NIH\/3T3 cells, mouse heart tissue,  HepG2 cells,  RAW 264.7 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:2000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nProgrammed cell death ligand 2 (PD-L2, also known as CD273, or B7-DC), is one of the B7 family molecules which are type I transmembrane proteins belonging to the immunoglobulin superfamily. PD-L2 was identified both by its homology to PD-L1 and by analysis of genes differentially expressed in libraries generated from dendritic cells (DC) and activated macrophages (PMID: 14515254). PD-L2 is a second ligand for PD-1, a costimulatory molecule that plays an inhibitory role in regulating T cell activation in the periphery.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse, rat\nCited Reactivity: human, mouse\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag13039 Product name: Recombinant human PDCD1LG2 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-273 aa of BC074766 Sequence: MIFLLLMLSLELQLHQIAALFTVTVPKELYIIEHGSNVTLECNFDTGSHVNLGAITASLQKVENDTSPHRERATLLEEQLPLGKASFHIPQVQVRDEGQYQCIIIYGVAWDYKYLTLKVKASYRKINTHILKVPETDEVELTCQATGYPLAEVSWPNVSVPANTSHSRTPEGLYQVTSVLRLKPPPGRNFSCVFWNTHVRELTLASIDLQSQMEPRTHPTWLLHIFIPSCIIAFIFIATVIALRKQLCQKLYSSKDTTKRPVTTTKREVNSAI Predict reactive species\nFull Name: programmed cell death 1 ligand 2\nCalculated Molecular Weight: 273 aa, 31 kDa\nObserved Molecular Weight: 40-50 kDa, 28 kDa\nGenBank Accession Number: BC074766\nGene Symbol: PD-L2\nGene ID (NCBI): 80380\nRRID: AB_2878523\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q9BQ51\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46868876918953,"sku":"18251-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-18251-1-ap","provider":"Iright","version":"1.0","type":"link"}