{"product_id":"proteintech-18797-1-ap","title":"Proteintech, 18797-1-AP, HSF4 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe HSF4 (18797-1-AP) by Proteintech is a Polyclonal antibody targeting HSF4 in WB, ELISA applications with reactivity to human,  mouse samples\n18797-1-AP targets HSF4 in WB, IHC, ELISA applications and shows reactivity with human,  mouse samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: HeLa cells, mouse skeletal muscle tissue,  human skeletal muscle tissue,  human heart tissue,  MCF-7 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:1000-1:4000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nHSF4 belongs to the HSF family. HSF4 is a DNA-binding protein that specifically binds heat shock promoter elements (HSE).  The isoform HSF4A represses transcription while the isoform HSF4B activates transcription. HSF4 is a homotrimer which exhibits constitutive DNA binding and forms trimers even in the absence of stress. It is expressed in heart, skeletal muscle, eye and brain, and at much lower levels in some other tissues. Mutation of HSF4 will cause lamellar cataract which is known as Marner type cataract (CAM). Lamellar cataract is an autosomal dominant common type of infantile cataract. Finger malformation is observed in some kindreds. Inheritance of these forms of cataract is autosomal dominant.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse\nCited Reactivity: human, mouse\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: heat shock transcription factor 4\nCalculated Molecular Weight: 53 kDa\nObserved Molecular Weight: 53-58 kDa\nGenBank Accession Number: BC130383\nGene Symbol: HSF4\nGene ID (NCBI): 3299\nRRID: AB_10598014\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q9ULV5\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46869411823785,"sku":"18797-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-18797-1-ap","provider":"Iright","version":"1.0","type":"link"}