{"product_id":"proteintech-18868-1-ap","title":"Proteintech, 18868-1-AP, PCYOX1 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe PCYOX1 (18868-1-AP) by Proteintech is a Polyclonal antibody targeting PCYOX1 in IHC, ELISA applications with reactivity to human, mouse, rat samples\n18868-1-AP targets PCYOX1 in IHC, ELISA applications and shows reactivity with human, mouse, rat samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive IHC detected in: human colon tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nImmunohistochemistry (IHC): IHC : 1:20-1:200\n\u003cb\u003eBackground Information\u003c\/b\u003e\nPCYOX1(Prenylcysteine oxidase 1) is also named as KIAA0908, PCL1, prenylcysteine lyase and belongs to the prenylcysteine oxidase family. The deduced 505-amino acid protein contains a predicted signal sequence, several transmembrane regions, and four potential N-glycosylation sites. It is a glycosylated enzyme involved in prenylated protein catabolism, releasing a free cysteine and a hydrophobic isoprenoid product. Immunofluorescence studies of PCYOX1 showed a nonnuclear punctate pattern, and PCYOX1 colocalized with lysosomal marker LAMP1 in HEK293 cells(PMID:10585463). The enzyme is isolated from bovine brain membranes and exhibits an apparent molecular mass of 63 kDa(PMID:9287348).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse, rat\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag4316 Product name: Recombinant human PCYOX1 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 155-505 aa of BC033815 Sequence: WVEDVLDKFMRIYRYQSHDYAFSSVEKLLHALGGDDFLGMLNRTLLETLQKAGFSEKFLNEMIAPVMRVNYGQSTDINAFVGAVSLSCSDSGLWAVEGGNKLVCSGLLQASKSNLISGSVMYIEEKTKTKYTGNPTKMYEVVYQIGTETRSDFYDIVLVATPLNRKMSNITFLNFDPPIEEFHQYYQHIVTTLVKGELNTSIFSSRPIDKFGLNTVLTTDNSDLFINSIGIVPSVREKEDPEPSTDGTYVWKIFSQETLTKAQILKLFLSYDYAVKKPWLAYPHYKPPEKCPSIILHDRLYYLNGIECAASAMEMSAIAAHNAALLAYHRWNGHTDMIDQDGLYEKLKTEL Predict reactive species\nFull Name: prenylcysteine oxidase 1\nCalculated Molecular Weight: 505 aa, 57 kDa\nGenBank Accession Number: BC033815\nGene Symbol: PCYOX1\nGene ID (NCBI): 51449\nRRID: AB_10598471\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q9UHG3\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887754236073,"sku":"18868-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-18868-1-ap","provider":"Iright","version":"1.0","type":"link"}