{"product_id":"proteintech-18884-1-ap","title":"Proteintech, 18884-1-AP, Glutaredoxin 5 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe Glutaredoxin 5 (18884-1-AP) by Proteintech is a Polyclonal antibody targeting Glutaredoxin 5 in WB, IF\/ICC, ELISA applications with reactivity to human, mouse samples\n18884-1-AP targets Glutaredoxin 5 in WB, IF\/ICC, ELISA applications and shows reactivity with human, mouse samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: HepG2 cells, MCF-7 cells,  mouse heart tissue\nPositive IF\/ICC detected in: MCF-7 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:2000\nImmunofluorescence (IF)\/ICC: IF\/ICC : 1:200-1:800\n\u003cb\u003eBackground Information\u003c\/b\u003e\nGlutaredoxin 5 (GLRX5) is an essential protein engaging in mitochondrial iron-sulfur cluster (ISC) transfers to iron regulatory protein (IRP), m-aconitase, and ferrochelatase. GLRX5 deficiency impairs heme biosynthesis, causing sideroblastic anemia and variant nonketotic hyperglycinemia in humans. Mutations of GLRX5 lead to distinct effects on downstream ISC biosynthesis and maturation.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag13445 Product name: Recombinant human GLRX5 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-157 aa of BC023528 Sequence: MSGSLGRAAAALLRWGRGAGGGGLWGPGVRAAGSGAGGGGSAEQLDALVKKDKVVVFLKGTPEQPQCGFSNAVVQILRLHGVRDYAAYNVLDDPELRQGIKDYSNWPTIPQVYLNGEFVGGCDILLQMHQNGDLVEELKKLGIHSTLLDEKKDQDSK Predict reactive species\nFull Name: glutaredoxin 5\nCalculated Molecular Weight: 157 aa, 17 kDa\nObserved Molecular Weight: 10-15 kDa\nGenBank Accession Number: BC023528\nGene Symbol: GLRX5\nGene ID (NCBI): 51218\nRRID: AB_3669306\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q86SX6\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887652294825,"sku":"18884-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-18884-1-ap","provider":"Iright","version":"1.0","type":"link"}