{"product_id":"proteintech-19538-1-ap","title":"Proteintech, 19538-1-AP, CXCR2 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe CXCR2 (19538-1-AP) by Proteintech is a Polyclonal antibody targeting CXCR2 in IHC, ELISA applications with reactivity to mouse samples\n19538-1-AP targets CXCR2 in IHC, IF, ELISA applications and shows reactivity with mouse samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive IHC detected in: mouse spleen tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nImmunohistochemistry (IHC): IHC : 1:50-1:500\n\u003cb\u003eBackground Information\u003c\/b\u003e\nCXCR2, also named as Cmkar2, Gpcr16, Il8rb or CD182, belongs to the G-protein coupled receptor 1 family. CXCR2 is a receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. CXCR2 binds to IL-8 with high affinity.  CXCR2 also binds with high affinity to CXCL3, GRO\/MGSA and NAP-2. This antibody is specific to mouse CXCR2.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: mouse\nCited Reactivity: mouse\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: interleukin 8 receptor, beta\nCalculated Molecular Weight: 41 kDa\nGenBank Accession Number: NM_009909\nGene Symbol: Cxcr2\nGene ID (NCBI): 12765\nRRID: AB_2878587\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: P35343\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46869529067689,"sku":"19538-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-19538-1-ap","provider":"Iright","version":"1.0","type":"link"}