{"product_id":"proteintech-19722-1-ap","title":"Proteintech, 19722-1-AP, SPTBN1-Specific Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe SPTBN1-Specific (19722-1-AP) by Proteintech is a Polyclonal antibody targeting SPTBN1-Specific in WB, IHC, IP, ELISA applications with reactivity to human, mouse, rat samples\n19722-1-AP targets SPTBN1-Specific in WB, IHC, IF, IP, CoIP, ELISA applications and shows reactivity with human, mouse, rat samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: mouse brain tissue, mouse kidney tissue,  mouse lung tissue\nPositive IP detected in: HEK-293 cells\nPositive IHC detected in: human liver cancer tissue, human lung tissue,  human kidney tissue,  human pancreas cancer tissue,  human normal colonNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:1000\nImmunoprecipitation (IP): IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate\nImmunohistochemistry (IHC): IHC : 1:50-1:500\n\u003cb\u003eBackground Information\u003c\/b\u003e\nSPTBN1 is the non-erythrocytic form of β-spectrin or β-fodrin. Spectrins are members of the superfamily of F-actin cross linking proteins that are important as scaffolding proteins for protein sorting, cell adhesion, and migration. Reduced expression of SPTBN1 has been found to correlate with shorter survival of patients with hepatocellular cancer, pancreatic cancer and other malignancies of the gastrointestinal tract, suggesting tumor suppression ability of this protein.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse, rat\nCited Reactivity: human, mouse\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: spectrin, beta, non-erythrocytic 1\nCalculated Molecular Weight: 275 kDa\nObserved Molecular Weight: 275 kDa\nGenBank Accession Number: NM_003128\nGene Symbol: SPTBN1\nGene ID (NCBI): 6711\nRRID: AB_10638469\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q01082\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46868973945001,"sku":"19722-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-19722-1-ap","provider":"Iright","version":"1.0","type":"link"}