{"product_id":"proteintech-20046-1-ap","title":"Proteintech, 20046-1-AP, MED13L Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe MED13L (20046-1-AP) by Proteintech is a Polyclonal antibody targeting MED13L in WB, ELISA applications with reactivity to human samples\n20046-1-AP targets MED13L in WB, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: K-562 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:1000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nMED13L, also named as KIAA1025, PROSIT240, THRAP2 and TRAP240L, belongs to the Mediator complex subunit 13 family. It is a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. MED13L is a mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. MED13L is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. This subunit may specifically regulate transcription of targets of the Wnt signaling pathway and SHH signaling pathway. The antibody has no cross reaction to MED13.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: mediator complex subunit 13-like\nCalculated Molecular Weight: 243 kDa\nObserved Molecular Weight: 240 kDa\nGenBank Accession Number: NM_015335\nGene Symbol: MED13L\nGene ID (NCBI): 23389\nRRID: AB_3085597\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q71F56\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887715766441,"sku":"20046-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-20046-1-ap","provider":"Iright","version":"1.0","type":"link"}