{"product_id":"proteintech-20695-1-ap","title":"Proteintech, 20695-1-AP, p300 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe p300 (20695-1-AP) by Proteintech is a Polyclonal antibody targeting p300 in WB, ELISA applications with reactivity to human, mouse samples\n20695-1-AP targets p300 in WB, IHC, IF, CoIP, ELISA applications and shows reactivity with human, mouse samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: HEK-293T cells, MCF-7 cells,  HeLa cells,  Jurkat cells,  RAW 264.7 cells,  PC-3 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:1000\n\u003cb\u003eBackground Information\u003c\/b\u003e\np300 is a 300 kDa global transcriptional coactivator with histone acetyltransferase (HAT) activity. p300 binds to chromosomal histones and modulates the chromatin conformation by acetylation of its histones, leading to activation of various gene transcriptions. p300 plays a critical role in DNA repair synthesis after DNA damage induced by ultraviolet or radiation. p300 is overexpressed in various types of cancer, which is associated with worse patient outcomes (PMID: 27322077).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse\nCited Reactivity: human, mouse\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: E1A binding protein p300\nCalculated Molecular Weight: 264 kDa\nObserved Molecular Weight: 300 kDa\nGenBank Accession Number: NM_001429\nGene Symbol: EP300\nGene ID (NCBI): 2033\nRRID: AB_3085614\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: Q09472\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46868958773417,"sku":"20695-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-20695-1-ap","provider":"Iright","version":"1.0","type":"link"}