{"product_id":"proteintech-20968-1-ap","title":"Proteintech, 20968-1-AP, CYP11B2 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe CYP11B2 (20968-1-AP) by Proteintech is a Polyclonal antibody targeting CYP11B2 in WB, IHC, IF\/ICC, ELISA applications with reactivity to human, mouse, pig samples\n20968-1-AP targets CYP11B2 in WB, IHC, IF\/ICC, ELISA applications and shows reactivity with human, mouse, pig samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: SKOV-3 cells, pig adrenal gland tissue\nPositive IHC detected in: human adrenal gland tissue, human kidney tissue,  human hepatocirrhosis tissue,  human liver cancer tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0\nPositive IF\/ICC detected in: SKOV-3 cells\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:200-1:1000\nImmunohistochemistry (IHC): IHC : 1:50-1:500\nImmunofluorescence (IF)\/ICC: IF\/ICC : 1:20-1:200\n\u003cb\u003eBackground Information\u003c\/b\u003e\nCYP11B2 (Cytochrome P450 11B2), also known as aldosterone synthase, is a member of the cytochrome P450 superfamily of enzymes.  CYP11B2 can only catalyze 11-deoxycorticosterone oxidation to produce corticosterone and further hydroxylation to ALD. CYP11B2 is an enzyme required for cortisol biosynthesis and is specifically expressed in aldosterone-producing tissue of the adrenal cortex and is overexpressed in aldosterone-producing adenomas (APA).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse, pig\nCited Reactivity: human, mouse\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: cytochrome P450, family 11, subfamily B, polypeptide 2\nCalculated Molecular Weight: 58 kDa\nObserved Molecular Weight: 48-50 kDa\nGenBank Accession Number: NM_000498\nGene Symbol: CYP11B2\nGene ID (NCBI): 1585\nRRID: AB_2878777\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: P19099\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46868996456617,"sku":"20968-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-20968-1-ap","provider":"Iright","version":"1.0","type":"link"}