{"product_id":"proteintech-21007-1-ap","title":"Proteintech, 21007-1-AP, Thyroid Hormone Receptor beta Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe Thyroid Hormone Receptor beta (21007-1-AP) by Proteintech is a Polyclonal antibody targeting Thyroid Hormone Receptor beta in WB, ELISA applications with reactivity to Mouse samples\n21007-1-AP targets Thyroid Hormone Receptor beta in WB, IHC, IF, ELISA applications and shows reactivity with Mouse samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: mouse retina tissue, mouse eye tissue\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:1000-1:6000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nThyroid hormone receptor beta (THRB), also known as ERBA2, NR1A2, and THR1, belongs to the nuclear hormone receptor family and NR1 subfamily. THRB is a nuclear hormone receptor that can act as a repressor or activator of transcription. Moreover, THRB is also a high-affinity receptor for thyroid hormones, including triiodothyronine and thyroxine. THRB is the most abundant THR isoform in the liver but is also expressed in other tissues and mediates the effects of THs on hepatic carbohydrate and lipid metabolism (PMID: 34884910).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: Mouse\nCited Reactivity: human, mouse\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag15210 Product name: Recombinant human THRB protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 112-461 aa of BC106929 Sequence: DKATGYHYRCITCEGCKGFFRRTIQKNLHPSYSCKYEGKCVIDKVTRNQCQECRFKKCIYVGMATDLVLDDSKRLAKRKLIEENREKRRREELQKSIGHKPEPTDEEWELIKTVTEAHVATNAQGSHWKQKRKFLPEDIGQAPIVNAPEGGKVDLEAFSHFTKIITPAITRVVDFAKKLPMFCELPCEDQIILLKGCCMEIMSLRAAVRYDPESETLTLNGEMAVTRGQLKNGGLGVVSDAIFDLGMSLSSFNLDDTEVALLQAVLLMSSDRPGLACVERIEKYQDSFLLAFEHYINYRKHHVTHFWPKLLMKVTDLRMIGACHASRFLHMKVECPTELFPPLFLEVFED Predict reactive species\nFull Name: thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)\nCalculated Molecular Weight: 476 aa, 54 kDa\nObserved Molecular Weight: 50 kDa\nGenBank Accession Number: BC106929\nGene Symbol: Thyroid Hormone Receptor beta\nGene ID (NCBI): 7068\nRRID: AB_3085632\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: P10828\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46869612822697,"sku":"21007-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-21007-1-ap","provider":"Iright","version":"1.0","type":"link"}