{"product_id":"proteintech-21671-1-ap","title":"Proteintech, 21671-1-AP, RHBDL3 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe RHBDL3 (21671-1-AP) by Proteintech is a Polyclonal antibody targeting RHBDL3 in WB, ELISA applications with reactivity to human samples\n21671-1-AP targets RHBDL3 in WB, ELISA applications and shows reactivity with human samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: SH-SY5Y cells, mouse brain tissue,  rat brain tissue\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:1000-1:8000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nRHBDL3 (Rhomboid-related protein 3) is involved in a process known as regulated intramembrane proteolysis (RIP), where proteins are cleaved within the membrane to release functional polypeptides from their membrane anchors. It is expressed in several structures, including the central nervous system, embryo ectoderm, reproductive system, sensory organ, and thymus. RHBDL3 is also a prognostic marker in Glioblastoma multiforme, indicating its potential role in cancer-related pathways. It is expressed in various cell lines, particularly in those related to neuronal function and visual perception, with low cancer specificity.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: CatNo: Ag16499 Product name: Recombinant human RHBDL3 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-160 aa of BC100975 Sequence: MGEHPSPGPAVAACAEAERIEELEPEAEERLPAAPEDHWKVLFDQFDPGNTGYISTGKFRSLLESHSSKLDPHKREVLLALADSHADGQIGYQDFVSLMSNKRSNSFRQAILQGNRRLSSKALLEEKGLSLSQRLIRHVAYETLPREIDRKWYYDSYTCC Predict reactive species\nFull Name: rhomboid, veinlet-like 3 (Drosophila)\nCalculated Molecular Weight: 404 aa, 45 kDa\nObserved Molecular Weight: 40 kDa\nGenBank Accession Number: BC100975\nGene Symbol: RHBDL3\nGene ID (NCBI): 162494\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: P58872\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46887784415401,"sku":"21671-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-21671-1-ap","provider":"Iright","version":"1.0","type":"link"}