{"product_id":"proteintech-21777-1-ap","title":"Proteintech, 21777-1-AP, TTF1\/NKX2-1 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe TTF1\/NKX2-1 (21777-1-AP) by Proteintech is a Polyclonal antibody targeting TTF1\/NKX2-1 in WB, ELISA applications with reactivity to human, mouse, rat samples\n21777-1-AP targets TTF1\/NKX2-1 in WB, IP, ELISA applications and shows reactivity with human, mouse, rat samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: HeLa cells, mouse brain tissue,  mouse lung tissue,  rat brain tissue\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:2000\n\u003cb\u003eBackground Information\u003c\/b\u003e\nNKX2-1, also named as NKX2A, TITF1 and TTF1, belongs to the NK-2 homeobox family.  It is a transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. NKX2-1 is crucial in the maintenance of the thyroid differentiation phenotype. It may play a role in lung development and surfactant homeostasis. Defects in NKX2-1 are the cause of benign hereditary chorea (BHC), choreoathetosis, hypothyroidism, and neonatal respiratory distress (CHNRD). The antibody is specific to NKX2-1.\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, mouse, rat\nCited Reactivity: human, mouse\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: NK2 homeobox 1\nCalculated Molecular Weight: 42 kDa\nObserved Molecular Weight: 45-50 kDa\nGenBank Accession Number: NM_003317\nGene Symbol: TTF1\nGene ID (NCBI): 7080\nRRID: AB_2878919\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: P43699\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46869506425001,"sku":"21777-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-21777-1-ap","provider":"Iright","version":"1.0","type":"link"}