{"product_id":"proteintech-22302-1-ap","title":"Proteintech, 22302-1-AP, COL6A6 Polyclonal antibody","description":"Size: 20ul \/ 150ul\nThe COL6A6 (22302-1-AP) by Proteintech is a Polyclonal antibody targeting COL6A6 in WB, IHC, ELISA applications with reactivity to human, Mouse samples\n22302-1-AP targets COL6A6 in WB, IHC, ELISA applications and shows reactivity with human, Mouse samples.\n\u003cb\u003eTested Applications\u003c\/b\u003e\nPositive WB detected in: mouse heart tissue, mouse skeletal muscle tissue\nPositive IHC detected in: mouse heart tissue, mouse lung tissueNote: suggested antigen retrieval withTE buffer pH 9.0;(*) Alternatively, antigen retrieval may be performed withcitrate buffer pH 6.0\n\u003cb\u003eRecommended dilution\u003c\/b\u003e\nWestern Blot (WB): WB : 1:500-1:2000\nImmunohistochemistry (IHC): IHC : 1:50-1:500\n\u003cb\u003eBackground Information\u003c\/b\u003e\nCollagen type VI alpha 6 chain (COL6A6) belongs to the collagen VI (COL6) family which acts as a vital role in the extracellular matrix. COL6A6 encodes a 2,262-amino acid protein that contains multiple von Willebrand factor domains and forms a component of the basal lamina of epithelial cells (PMID: 33747955).  COL6A6 is a novel tumor suppressor gene in NSCLC and can serve as a potentially valuable prognostic biomarker and therapeutic target for NSCLC (PMID: 35116307).\n\u003cb\u003eSpecification\u003c\/b\u003e\nTested Reactivity: human, Mouse\nCited Reactivity: human, mouse\nHost \/ Isotype: Rabbit \/ IgG\nClass: Polyclonal\nType: Antibody\nImmunogen: Peptide Predict reactive species\nFull Name: collagen type VI alpha 6\nCalculated Molecular Weight: 247 kDa\nObserved Molecular Weight: 167 kDa, 250 kDa\nGenBank Accession Number: NM_001102608\nGene Symbol: COL6A6\nGene ID (NCBI): 131873\nRRID: AB_3085695\nConjugate: Unconjugated\nForm: Liquid\nPurification Method: Antigen affinity purification\nUNIPROT ID: A6NMZ7\nStorage Buffer: PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.\nStorage Conditions: Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage. 20ul sizes contain 0.1% BSA.","brand":"Proteintech","offers":[{"title":"Default Title","offer_id":46869526118569,"sku":"22302-1-AP","price":0.99,"currency_code":"USD","in_stock":true}],"url":"https:\/\/iright.com\/ar\/products\/proteintech-22302-1-ap","provider":"Iright","version":"1.0","type":"link"}